Relations between open-field- elevated plus-maze- and emergence tests as displayed by C57 and BL6J and BALB and c mice-

Authors
R. Lalonde, C. Strazielle.


Lab
Centre Hospitalier de l’Université de Montréal/St-Luc, Unité de Recherche en Sciences Neurologiques, Montréal, Québec, Canada ; Université Henri Poincaré, Laboratoire de Pathologie Moléculaire et Cellulaire en Nutrition, Vandoeuvre-les-Nancy, France.

Journal
Journal of Neuroscience Methods

Abstract
The relations between open-field, elevated plus-maze, and emergence tests were examined in two strains of mice. In the open-field, C57BL/6J mice had more ambulatory movements and rears but not stereotyped movements relative to BALB/c. In addition, C57BL/6J mice entered more often than BALB/c into enclosed and open arms of the elevated plus-maze. When placed inside a large enclosure, C57BL/6J mice emerged more quickly than BALB/c from a small toy object. In the entire series of mice, ambulation and rears in the open-field were linearly correlated with open and enclosed arm visits in the elevated plus-maze. Ambulatory movements and rears were also correlated with emergence latencies. In contrast, stereotyped movements were correlated with emergence latencies, but not with any elevated plus-maze value. These results specify the extent and limits of association between the three tests.

BIOSEB Instruments Used:
Infrared Actimeter (LE8815)

Produits associés

DEMANDE DE PUBLICATION

Merci de votre intérêt pour notre gamme de produits et de votre demande pour cette publication qui vous sera envoyée si l'équipe de recherche et la revue le permettent. Notre équipe commerciale vous contactera dans les plus brefs délais.