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Système modulaire: enregistrement de O2 et CO2
Référence : OXYLET
Catégorie : Métabolisme & Nutrition
Système modulaire permettant l'intégration du métabolisme respiratoire,
de l'apport de nourriture et de boisson, de l'activité spontanée et
de la station debout par l'animal dans des cages spécifiquement adaptées
Présentation
Le métabolisme respiratoire est évalué au moyen de la calorimétrie indirecte, un système optimisé pour les études sur les rongeurs de laboratoire (souris et rats).
Principe de fonctionnement
L'apport de nourriture et de boissons et l'activité sont évalués à l'aide d'un de capteur de poids. Cette technologie permet l'évaluation continue de consommation de nourriture et de boissons par l'animal, ainsi que de l'activité spontanée avec la plus grande précision.
L'évaluation de la posture debout exige simplement un supplément infrarouge (IR) relié au châssis du système. La conception modulaire permet facilement l'extension du système pour l'ajout d'une des options.
Le chercheur peut sélectionner uniquement les composants correspondant à son intérêt initial ... mais avec la possibilité d'en ajouter d'autres à une date ultérieure.
Des configurations spéciales de ce système sont disponibles pour effectuer des études de calorimétrie avec les rats nouveau-nés ou au cours d'expériences sur tapis roulant.
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| Oxylet est un système complet | Physiocage modulaire pour Rat (Système complet) |
Une des principales innovations de ce système est que l’OXYLET ne nécessite pas d’unités de séchage ou de colonnes de dessiccation qui peuvent être trouvées dans des systèmes de technologie plus ancienne.
Un autre point fort est l’utilisation de capteurs à haute sensibilité avec un temps de réponse très rapide à la fois pour des mesures de O2 et de CO2.
Des cages étanches standards permettent de suivre le métabolisme des rongeurs pendant plusieurs heures. Des cages étanches à l’air, avec des distributeurs alimentaires et de boissons, lorsque des études de plusieurs jours doivent être effectuées, peuvent être proposées.
Paramètres mesurés
• Consommation d'O2
• Production de CO2
• Quotient respiratoire
• Échanges énergétiques
• Consommation d'aliments sur des intervalles de temps définis par l'utilisateur
• Consommation de boisson sur des intervalles de temps définis par l'utilisateur
• Moyenne d'activité spontanée sur des intervalles de temps définis par l'utilisateur
• Nombre de posture debout sur des intervalles de temps définis par l'utilisateur 
Principales caractéristiques
• Système facilement extensible disponible en différentes configurations
• Capteurs très sensibles et stables pour les mesures d'O2 et de CO2
• Système optimisé pour le rat et la souris
• Capteur laser pour n'avoir qu'une faible influence de l'humidité de l'air sur la mesure de gaz O2/CO2
• Technologie de poids nouvellement adaptée avec des capteurs pour le suivi de la prise de nourriture et de boisson et de l'activité spontanée, fournissant une plus grande précision
• Distributeurs de nourriture et de boissons externes afin d'éviter toute influence sur l'espace de vie de l'animal ainsi que les artefacts indésirables
• Registres de la nourriture et de la boisson absorbées et leur gaspillage par le biais de systèmes spécifiquement adaptés
• La posture debout peut être évaluée à l'aide d'un cadre infrarouge supplémentaire
Domaines d'application
Cet appareil est spécialement recommandé pour les études dans les domaines suivants :
• Anorexie et ses traitements
• Dépendance ou aversion pour des substances spécifiques
• Mécanismes de faim et de satiété, associés à l’énergie dispensée
• Diabète et son traitement
• ...
OXYLET
Fiche technique
- Applications
- Métabolisme
Système Nerveux Central (SNC)
Système moteur
Système musculaire
Thématiques transversales
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[url] => https://bioseb.com/fr/news/nonalcoholic-hepatic-steatosis-in-zucker-diabetic-rats--spontaneous-evolution-and-effects-of-metformin-and-fenofibrate--n413
[title] => Nonalcoholic hepatic steatosis in Zucker diabetic rats- spontaneous evolution and effects of metformin and fenofibrate-
[paragraph_crop] => Nonalcoholic hepatic steatosis in Zucker diabetic rats: spontaneous evolution and effects of [...]
[image_presente] =>
[date] => 2009-07-01 00:00:00
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[id] => 129
[url] => https://bioseb.com/fr/news/fxr-deficiency-confers-increased-susceptibility-to-torpor--n129
[title] => FXR-deficiency confers increased susceptibility to torpor-
[paragraph_crop] => FXR-deficiency confers increased susceptibility to torpor.
[image_presente] =>
[date] => 2007-11-13 00:00:00
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[94] => Array
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[id] => 94
[url] => https://bioseb.com/fr/news/resistance-to-high-fat-diet-induced-obesity-and-sexual-dimorphism-in-the-metabolic-responses-of-transgenic-mice-with-moderate-uncoupling-protein-3-overexpression-in-glycolytic-skeletal-muscles--n94
[title] => Resistance to high-fat-diet-induced obesity and sexual dimorphism in the metabolic responses of transgenic mice with moderate uncoupling protein 3 overexpression in glycolytic skeletal muscles-
[paragraph_crop] => Resistance to high-fat-diet-induced obesity and sexual dimorphism in the metabolic responses [...]
[image_presente] =>
[date] => 2007-10-30 00:00:00
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[title] => Fonctions squelettales
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[title] => Métabolisme
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[title] => Prise alimentaire / Nutrition
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[2] => Array
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[title] => Publications
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[20] => Array
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[title] => Système musculaire
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[id] => 112
[url] => https://bioseb.com/fr/news/-n112
[title] =>
[paragraph_crop] =>
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[date] => 2007-04-01 00:00:00
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[title] => Adiposité
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[title] => Dépenses énergétiques
[link_rewrite] => Depenses-energetiques
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[title] => Diabète, Insuline & Glucose
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[107] => Array
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[id] => 107
[url] => https://bioseb.com/fr/news/involvement-of-cholecystokinin-2-receptor-in-food-intake-regulation--hyperphagia-and-increased-fat-deposition-in-cholecystokinin-2-receptor-deficient-mice-n107
[title] => Involvement of Cholecystokinin 2 Receptor in Food Intake Regulation- Hyperphagia and Increased Fat Deposition in Cholecystokinin 2 Receptor-Deficient Mice
[paragraph_crop] => Involvement of Cholecystokinin 2 Receptor in Food Intake Regulation: Hyperphagia and Increased [...]
[image_presente] =>
[date] => 2007-03-01 00:00:00
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[title] => Prise alimentaire / Nutrition
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[title] => Publications
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[42] => Array
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[id] => 42
[url] => https://bioseb.com/fr/news/dysregulation-of-energy-homeostasis-in-mice-overexpressing-insulin-like-growth-factor-binding-protein-6-in-the-brain--n42
[title] => Dysregulation of energy homeostasis in mice overexpressing insulin-like growth factor-binding protein 6 in the brain-
[paragraph_crop] => Dysregulation of energy homeostasis in mice overexpressing insulin-like growth factor-binding [...]
[image_presente] =>
[date] => 2005-06-30 00:00:00
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[title] => Fonctions cérébrales
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[title] => Moelle épinière
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[title] => Publications
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[title] => Système Nerveux Central (SNC)
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)
1Nombre de publications:
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