Activité, Système Moteur & Coordination
Douleur - Allodynie/Hyperalgésie Thermique
Douleur - Spontanée - Déficit de Posture
Douleur - Allodynie/Hyperalgésie Mécanique
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Apprentissage/Mémoire - Attention - Addiction
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Métabolisme & Nutrition
Kits contextuels pour T2CT - Double aversion & CPP
Les Kits contextuels pour T2CT ont été conçus pour enrichir les études de préférence de place...
Douleur
Système Nerveux Central (SNC) 
Neurodégénérescence
Système sensoriel
Système moteur
Troubles de l'humeur
Autres pathologies
Système musculaire
Articulations
Métabolisme
Thématiques transversales
Congrès & Meetings 
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Plaque froid et chaud
Référence : BIO-CHP
Catégorie : Douleur - Allodynie/Hyperalgésie Thermique
Instrument de test de la sensibilité de l'animal à la douleur résultant de l'exposition à la chaleur ou au froid: la plaque froid et chaud de Bioseb est un instrument innovant ouvrant de nouveaux champs d'investigation pour vos recherches en analgésie et nociception, et un outil efficace pour le screening de substances analgésiques basé sur les modèles de rat ou souris.
Présentation
La plaque 'froid et chaud' de Bioseb est un instrument innovant ouvrant de nouveaux champs d'investigation pour vos recherches en analgésie et nociception en vous permettant de tester la sensibilité de l'animal (rat ou souris) à la douleur résultant de l'exposition à la chaleur ou au froid.
La plaque 'froid et chaud' de Bioseb utilise une plaque métallique qui peut être, au choix, chauffée à 55 °C ou refroidie à -2°C (pour une température ambiante de 20 à 25ºC). Un thermostat électrique maintient la plaque à température et l'écran digital affiche la température courante.
La Plaque 'Froid et Chaud' de Bioseb est conçue pour une utilisation très simple, et les températures réglées sont atteintes très rapidement (par exemple: de l'ambiante à 4°C, la valeur de seuil la plus courante, moins de 10 minutes sont nécessaires, et seulement 5 minutes de 4°C à 55°C). Du point de vue métrologique, la plaque est précise à moins de 0,5°C près (Standard Métrologique Européen) et parfaitement constante sur toute la surface. La température pré-réglée ne varie pas de plus de 0,1°C lorsqu'un rat de 400g est placé sur la plaque, et le retour à la température voulue est quasi-instantané.
Principe de fonctionnement
La sensibilité de l'animal (rat ou souris) à la douleur résultant de l'exposition à la chaleur ou au froid est testée en le plaçant sur la surface de la plaque 'froid et chaud' et en démarrant le chronomètre intégré à l'unité. L'opérateur stoppe le chronomètre au moment où l''animal soulève sa patte, réagissant à l'inconfort provoqué par des températures incomodantes. L'écran digitale affiche alors le temps écoulé (en secondes) jusqu'à la réaction de l'animal. Le temps de réaction est une indication de la résistance de l'animal à la douleur et est utilisé pour évaluer l'efficacité de substances analgésiques.
L'opérateur peut démarrer ou stopper le chronomètre avec la commande disponible sur la face avant ou avec la pédale incluse, qui libère les mains pendant l'opération.
BIO-CHP
Fiche technique
- Dimensions - Cage animal
- Dimensions de la Plaque 165 x165 mm
- Dimensions globales
- Dimensions de la cage 165x165x300 mm
- Alimentation
- 110V/220V automatique, 100W
- Plage
- de -2 degrés C. à 55 degrés C (pour une température ambiante de 20 à 25 degrés C., 50 % HR)
- Applications
- Cognitive performance
Douleur
Fonctions de motricité générale
Métabolisme
Neurodégénérescence
Système Nerveux Central (SNC)
Système moteur
Système sensoriel
Thématiques transversales
Troubles de l'humeur - Précision
- Overshoot max sur la consigne 0.5°C
Précision +/- 0.5 degrés C.
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[title] => Sensory Deficits in mice with Lateral Spinal Cord Hemisection Mimic the Brown-Sequard Syndrome
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[title] => Characterization of a mouse model of osteoarticular infection using clinical isolates of Staphylococcus aureus
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[title] => Decreased opioid receptor availability and impaired neurometabolic coupling as signatures of morphine tolerance in male rats- A positron emission tomography study
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[title] => 5-HT3a receptor contributes to neuropathic pain by regulating central sensitization in a rat with brachial plexus avulsion
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[title] => Neuroprotective Effect of Polyvalent Immunoglobulins on Mouse Models of Chemotherapy-Induced Peripheral Neuropathy
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[title] => The Overexpression of Insulin-Like Growth Factor-1 and Neurotrophin-3 Promote Functional Recovery and Alleviate Spasticity After Spinal Cord Injury
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[title] => Trace Amine-Associated Receptor 2 Is Expressed in the Limbic Brain Areas and Is Involved in Dopamine Regulation and Adult Neurogenesis
[paragraph_crop] => Trace Amine-Associated Receptor 2 Is Expressed in the Limbic Brain Areas and Is Involved in [...]
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[title] => Protein Tyrosine Phosphatase Receptor Type D Regulates Neuropathic Pain After Nerve Injury via the STING-IFN-I Pathway
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[date] => 2021-09-30 00:00:00
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[url] => https://bioseb.com/fr/news/pain-hypersensitivity-in-a-pharmacological-mouse-model-of-attention-deficithyperactivity-disorder-adhd-n1465
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[date] => 2021-04-23 00:00:00
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[title] => TRPV1 is involved in the antinociceptive effects of resveratrol in paclitaxel-induced neuropathic pain
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[title] => Preventing oxaliplatin_induced neuropathic pain- Using berberine to inhibit the activation of NF_kappaB and release of pro_inflammatory cytokines in dorsal root ganglions in rats Preventing oxaliplatin_induced neuropathic pain- Using berberine to inhibit
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[title] => Selective activation of metabotropic glutamate receptor 7 blocks paclitaxel-induced acute neuropathic pain and suppresses spinal glial reactivity in rats
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[title] => Puerarin alleviates vincristine-induced neuropathic pain and neuroinflammation via inhibition of nuclear factor-kappaB and activation of the TGF-beta-and-Smad pathway in rats
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[title] => Curcumin-cyclodextrin and cellulose Nanocrystals Improve the Phenotype of Charcot-Marie-Tooth-1A Transgenic Rats Through the Reduction of Oxidative Stress
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[date] => 2020-09-25 00:00:00
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[url] => https://bioseb.com/fr/news/deep-posteromedial-cortical-rhythm-in-dissociation-n1305
[title] => Deep posteromedial cortical rhythm in dissociation
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[image_presente] =>
[date] => 2020-09-16 00:00:00
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[url] => https://bioseb.com/fr/news/forward-genetics-identifies-a-novel-sleep-mutant-with-sleep-state-inertia-and-rem-sleep-deficits-n1297
[title] => Forward genetics identifies a novel sleep mutant with sleep state inertia and REM sleep deficits
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[date] => 2020-08-12 00:00:00
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[url] => https://bioseb.com/fr/news/behavioral-tests-assessing-neuropsychiatric-phenotypes-in-adolescent-mice-reveal-strain--and-sex-specific-effects-n1287
[title] => Behavioral tests assessing neuropsychiatric phenotypes in adolescent mice reveal strain- and sex-specific effects
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[date] => 2020-07-09 00:00:00
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[url] => https://bioseb.com/fr/news/baicalin-prevents-the-upregulation-of-trpv1-in-dorsal-root-ganglion-and-attenuates-chronic-neuropathic-pain-n1286
[title] => Baicalin prevents the up_regulation of TRPV1 in dorsal root ganglion and attenuates chronic neuropathic pain
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[date] => 2020-06-01 00:00:00
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[url] => https://bioseb.com/fr/news/chronic-morphine-regulates-trpm8-channels-via-mor-pkcbeta-signaling-n1264
[title] => Chronic morphine regulates TRPM8 channels via MOR-PKCbeta signaling
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[date] => 2020-04-14 00:00:00
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[url] => https://bioseb.com/fr/news/testosteroneandrogen-receptor--the-steroid-link-inhibiting-trpm8mediated-cold-sensitivity-n1262
[title] => Testosterone_androgen receptor- The steroid link inhibiting TRPM8_mediated cold sensitivity
[paragraph_crop] => Testosterone_androgen receptor: The steroid link inhibiting TRPM8_mediated cold sensitivity
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[date] => 2020-03-18 00:00:00
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[url] => https://bioseb.com/fr/news/loss-of-bhlha9-impairs-thermotaxis-and-formalin-evoked-pain-in-a-sexually-dimorphic-manner-n1214
[title] => Loss of bhlha9 Impairs Thermotaxis and Formalin-Evoked Pain in a Sexually Dimorphic Manner
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[url] => https://bioseb.com/fr/news/baicalin-ameliorates-bone-cancer-pain-by-suppressing-trpv1-in-rat-dorsal-root-ganglia--n1208
[title] => Baicalin Ameliorates Bone Cancer Pain by Suppressing TRPV1 in Rat Dorsal Root Ganglia
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[image_presente] =>
[date] => 2020-01-08 00:00:00
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[url] => https://bioseb.com/fr/news/analgesic-and-antiallodynic-activity-of-novel-anticonvulsant-agents-derived-from-3-benzhydryl-pyrrolidine-2-5-dione-in-mouse-models-of-nociceptive-and-neuropathic-pain-n1203
[title] => Analgesic and antiallodynic activity of novel anticonvulsant agents derived from 3-benzhydryl-pyrrolidine-2-5-dione in mouse models of nociceptive and neuropathic pain
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[date] => 2019-12-19 00:00:00
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[url] => https://bioseb.com/fr/news/bioscreening-of-the-spacerized-complex-bis--2-pyridyl--3--1--2--4-triazolyl--propane-and-11-hydroxy-1--1-ethylidenediphosphonic-acid-n1189
[title] => Bioscreening of the spacerized complex BIS -2-Pyridyl--3--1- 2- 4-Triazolyl- propane and 11-Hydroxy-1- 1-Ethylidenediphosphonic acid
[paragraph_crop] => Bioscreening of the spacerized complex BIS (2-Pyridyl)-3-(1, 2, 4-Triazolyl) propane and [...]
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[url] => https://bioseb.com/fr/news/effect-of-1-hydroxy-1-1-ethylidendiphosphone-acid--bis-2-pyridyl-1-2-4-triazolyl-3-propane-and-their-adduct-on-the-pain-sensitivity-of-rats-pyridyl-1-2-4-triazolyl-3-propane-and-their-adduct-on-the-pain-sensitivity-of-rats-n1150
[title] => EFFECT OF 1-HYDROXY-1-1-ETHYLIDENDIPHOSPHONE ACID- BIS-2-PYRIDYL-1-2-4-TRIAZOLYL-3-PROPANE AND THEIR ADDUCT ON THE PAIN SENSITIVITY OF RATS PYRIDYL-1-2-4-TRIAZOLYL-3-PROPANE AND THEIR ADDUCT ON THE PAIN SENSITIVITY OF RATS
[paragraph_crop] => EFFECT OF 1-HYDROXY-1,1-ETHYLIDENDIPHOSPHONE ACID, BIS(2-PYRIDYL-1,2,4-TRIAZOLYL-3)PROPANE AND [...]
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[date] => 2019-08-01 00:00:00
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[title] => Effect of 1-Hydroxy-1-1-thylidendiphosphone Acid- Bis-2-Pyridyl-1-2-4-Triazolyl-3-Propane and their adduct on the pain sensitivty of Rats
[paragraph_crop] => Effect of 1-Hydroxy-1,1-thylidendiphosphone Acid, Bis(2-Pyridyl-1,2,4-Triazolyl-3)Propane and [...]
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[url] => https://bioseb.com/fr/news/cerebral-expression-of-glial-fibrillary-acidic-protein--ubiquitin-carboxy-terminal-hydrolase-l1--and-matrix-metalloproteinase-9-after-traumatic-brain-injury-and-secondary-brain-insults-in-rats-n1140
[title] => Cerebral Expression of Glial Fibrillary Acidic Protein- Ubiquitin Carboxy-Terminal Hydrolase-L1- and Matrix Metalloproteinase 9 After Traumatic Brain Injury and Secondary Brain Insults in Rats
[paragraph_crop] => Cerebral Expression of Glial Fibrillary Acidic Protein, Ubiquitin Carboxy-Terminal [...]
[image_presente] =>
[date] => 2019-04-25 00:00:00
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[url] => https://bioseb.com/fr/news/the-guanine-nucleotide-exchange-factor--spata13--influences-social-behaviour-and-nocturnal-activity-n1126
[title] => The guanine nucleotide exchange factor- Spata13- influences social behaviour and nocturnal activity
[paragraph_crop] => The guanine nucleotide exchange factor, Spata13, influences social behaviour and nocturnal activity
[image_presente] =>
[date] => 2019-04-24 00:00:00
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[title] => Effects of resveratrol in the signaling of neuropathic pain involving P2X3 in the dorsal root ganglion of rats
[paragraph_crop] => Effects of resveratrol in the signaling of neuropathic pain involving P2X3 in the dorsal root [...]
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[title] => Huachansu suppresses TRPV1 up-regulation and spinal astrocyte activation to prevent oxaliplatin-induced peripheral neuropathic pain in rats
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[image_presente] =>
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[title] => Amylin- a peptide expressed by nociceptors- modulates chronic neuropathic pain
[paragraph_crop] => Amylin, a peptide expressed by nociceptors, modulates chronic neuropathic pain
[image_presente] =>
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[title] => Cinobufacini protects against paclitaxel-induced peripheral neuropathic pain and suppresses TRPV1 up-regulation and spinal astrocyte activation in rats
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[image_presente] =>
[date] => 2018-12-01 00:00:00
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[title] => Increased Nociceptive Responses in Streptozotocin-Induced Diabetic Rats and the Related Expression of Spinal NR2B Subunit of N-methyl-D-aspartate Receptors
[paragraph_crop] => Increased Nociceptive Responses in Streptozotocin-Induced Diabetic Rats and the Related [...]
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[title] => Itch induced by peripheral mu opioid receptors is dependent on TRPV1-expressing neurons and alleviated by channel activation
[paragraph_crop] => Itch induced by peripheral mu opioid receptors is dependent on TRPV1-expressing neurons and [...]
[image_presente] =>
[date] => 2018-10-19 00:00:00
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[title] => Docking and pharmacodynamic studies on hGAT1 inhibition activity in the presence of selected neuronal and astrocytic inhibitors
[paragraph_crop] => Docking and pharmacodynamic studies on hGAT1 inhibition activity in the presence of selected [...]
[image_presente] =>
[date] => 2018-10-01 00:00:00
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[title] => Induction of brain Nrf2-HO-1 pathway and antinociception after different physical training paradigms in mice
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[image_presente] =>
[date] => 2018-09-15 00:00:00
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[title] => Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration
[paragraph_crop] => Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for [...]
[image_presente] =>
[date] => 2018-08-14 00:00:00
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[title] => Longitudinal Structural and Functional Brain Network Alterations in a Mouse Model of Neuropathic Pain
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[date] => 2018-04-20 00:00:00
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[title] => Wider range of allodynia in a rat model of repeated dural nociception compared with infraorbital nerve chronic constriction injury
[paragraph_crop] => Wider range of allodynia in a rat model of repeated dural nociception compared with [...]
[image_presente] =>
[date] => 2018-02-18 00:00:00
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[title] => Novel analgesic effects of melanin-concentrating hormone on persistent neuropathic and inflammatory pain in mice
[paragraph_crop] => Novel analgesic effects of melanin-concentrating hormone on persistent neuropathic and [...]
[image_presente] =>
[date] => 2018-01-15 00:00:00
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[title] => Inhibition of toll-like receptor 4 alleviates hyperalgesia induced by acute dural inflammation in experimental migraine
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[image_presente] =>
[date] => 2018-01-08 00:00:00
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[url] => https://bioseb.com/fr/news/molecular-prerequisites-for-diminished-cold-sensitivity-in-ground-squirrels-and-hamsters-n922
[title] => Molecular Prerequisites for Diminished Cold Sensitivity in Ground Squirrels and Hamsters
[paragraph_crop] => Molecular Prerequisites for Diminished Cold Sensitivity in Ground Squirrels and Hamsters
[image_presente] =>
[date] => 2017-12-19 00:00:00
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[title] => Potentiation of morphine-induced antinociception and locomotion by citalopram is accompanied by anxiolytic-like effects
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[image_presente] =>
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[url] => https://bioseb.com/fr/news/brain-natriuretic-peptide-expressing-sensory-neurons-are-not-involved-in-acute--inflammatory--or-neuropathic-pain-n950
[title] => Brain natriuretic peptide-expressing sensory neurons are not involved in acute- inflammatory- or neuropathic pain
[paragraph_crop] => Brain natriuretic peptide-expressing sensory neurons are not involved in acute, inflammatory, [...]
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[date] => 2017-09-08 00:00:00
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[title] => Candesartan prevents resiniferatoxin-induced sensory small-fiber neuropathy in mice by promoting angiotensin II-mediated AT2 receptor stimulation
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[title] => The Nav1- 9 Channel Is a Key Determinant of Cold Pain Sensation and Cold Allodynia
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[title] => Oligodendrocyte ablation triggers central pain independently of innate or adaptive immune responses in mice
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[title] => Neuroprotective Effect of Erythropoietin against Pressure Ulcer in a Mouse Model of Small Fiber Neuropathy
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[title] => Bidirectional integrative regulation of Cav1-2 calcium channel by microRNA miR-103- role in pain-
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[title] => Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors-
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[title] => Dissecting the functional significance of endothelin A receptors in peripheral nociceptors in vivo via conditional gene deletion-
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[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
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[13] => Array
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[id_prestablog_categorie] => 13
[title] => Système sensoriel
[link_rewrite] => Systeme-sensoriel
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[201] => Array
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[id] => 201
[url] => https://bioseb.com/fr/news/the-mechano-activated-k-channels-traak-and-trek-1-control-both-warm-and-cold-perception--n201
[title] => The mechano-activated K channels TRAAK and TREK-1 control both warm and cold perception-
[paragraph_crop] => The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception.
[image_presente] =>
[date] => 2009-05-06 00:00:00
[categories] => Array
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[id_prestablog_categorie] => 10
[title] => Douleur
[link_rewrite] => Douleur
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[27] => Array
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[id_prestablog_categorie] => 27
[title] => Douleurs générales
[link_rewrite] => Douleurs-generales
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[48] => Array
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[id_prestablog_categorie] => 48
[title] => Perception du chaud et du froid
[link_rewrite] => Perception-du-chaud-et-du-froid
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[2] => Array
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[title] => Publications
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[title] => Système sensoriel
[link_rewrite] => Systeme-sensoriel
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[187] => Array
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[id] => 187
[url] => https://bioseb.com/fr/news/asic3--a-sensor-of-acidic-and-primary-inflammatory-pain--n187
[title] => ASIC3- a sensor of acidic and primary inflammatory pain-
[paragraph_crop] => ASIC3, a sensor of acidic and primary inflammatory pain.
[image_presente] =>
[date] => 2008-11-19 00:00:00
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[title] => Domaines de recherche divers
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[id_prestablog_categorie] => 2
[title] => Publications
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