Activité, Système Moteur & Coordination
Douleur - Allodynie/Hyperalgésie Thermique
Douleur - Spontanée - Déficit de Posture
Douleur - Allodynie/Hyperalgésie Mécanique
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Apprentissage/Mémoire - Attention - Addiction
Physiologie & Recherche Respiratoire
Métabolisme & Nutrition
Kits contextuels pour T2CT - Double aversion & CPP
Les Kits contextuels pour T2CT ont été conçus pour enrichir les études de préférence de place...
Douleur
Système Nerveux Central (SNC) 
Neurodégénérescence
Système sensoriel
Système moteur
Troubles de l'humeur
Autres pathologies
Système musculaire
Articulations
Métabolisme
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Congrès & Meetings 
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Von Frey Électronique - Sans Fil
Référence : BIO-EVF-WRS
Catégorie : Douleur - Allodynie/Hyperalgésie Mécanique
Une solution rapide pour déterminer le seuil de sensibilité à la douleur mécanique chez les rongeurs (rats et souris). Maintenant en version sans-fil, pour être libéré des câbles!
Cet instrument électronique précis et simple d'utilisation est le test de référence pour vos recherches en analgésie, nociception, neuropathies et douleurs post-opératoires
Présentation
Les 16 années d’expérience de BIOSEB en instrumentation pour le test de Von Frey nous permettent de vous proposer un standard dans la mesure des seuils de sensibilité à la douleur mécanique chez les rongeurs (rats et souris).
Etudié pour améliorer la qualité des résultats et faciliter la prise de mesure comparés aux filaments de Von Frey qui demandent de nombreuses sollicitations pour chaque valeur et introduisent un stress chez l’animal, le test de Von Frey Electronique permet d’obtenir le seuil de sensibilité mécanique en une seule mesure.
Cette valeur, mesurée avec une résolution de 0.1 grammes grâce à un capteur de précision, permet de réduire le temps d’expérimentation et offre une meilleure répétabilité entre les différentes séries. Les résultats sont affichés sur un large écran rétro-éclairé. L'instrument électronique présente aussi l’avantage de n’avoir aucune dérive lié à la température ou à l’hygrométrie.
La plage étendue du capteur de mesure permet de travailler avec un grand nombre d’espèces (Rats, Souris, Homme…) avec le même instrument.
La dernière version du Von Frey Electronique intègre une nouvelle poignée de mesure intégralement repensée. Elle est plus facile à prendre en main mais aussi plus équilibrée de façon à simplifier la stimulation. Le confort d’utilisation réduit la fatigue de l’opérateur et diminue les tensions liées aux longues sessions de mesure sur un grand nombre d’animaux.La poignée intègre un nouveau capteur, plus précis et plus rigide, donc moins sensible au mouvements de l’opérateur. 
Principes de fonctionnement
L’Instrument de Von Frey Electronique est composé d’une unité d’affichage électronique ainsi que d’une poignée de stimulation. Une pédale est aussi livrée pour la remise à 0 de la mesure. Une boite de 10 pointes en plastique interchangeables est fournie.
L’expérimentateur prend en main la poignée de l’appareil et stimule avec la pointe dédiée la zone d’intérêt.
• Stimulation sous la patte du rongeur :
La stimulation est généralement effectuée sur les patte arrières du rongeur. Le retrait de la patte causé par la stimulation mécanique est enregistré comme la réponse à ce stimulus. La force maximale appliquée avec l’appareil, correspondant à la valeur nécessaire pour le retrait de la patte, est sauvegardée par le système et affichée sur l’écran de l'unité électronique du Von Frey, avec une résolution de 0.1 gramme. Une pointe différente est utilisée pour le rat (pointe en plastique dur) et pour la souris (pointe souple).
• Utilisation spécifique pour l’utilisation chez le patient :
L’appareil, dans sa version dédiée à une usage chez l’Humain, est livré avec un bouton dit 'bouton patient', permettant au patient recevant la stimulation de figer lui-même la mesure sur l’écran de l’instrument lorsque le seuil désiré (sensibilité, douleur) est atteint.
NOUVEAU: Sans fil
Une gamme complète d'instruments Bioseb, incluant le Von Frey Électronique, comprend désormais notre nouvelle technologie sans fil: grâce au boîtier sans fi placé sur le poignet de l'opérateur, il n'y a plus de câble entre la console éléctronique de l'écran et les capteurs
Cette nouvelle technologie sans fil offre de nombreux avantages:
• Mailleure liberté de mouvement: plus de câbes agaçants !
• Une configuration flexible pour votre laboratoire : concevez votre espace de travail sans limites
• Libérez vous des contraintes physiques : concentrez vous sur votre expérience !
Options facilitant la tâche de l'opérateur
• 'Bouton - patient' permet de figer la valeur du seuil (lors d'expérimentation clinique )
• Liaison RS232 permet de transférer la valeur affichée sur un ordinateur
• Tablette tactile pour affichage vidéo
• Logiciel BIO-CIS2 (pour PC sous Windows 7 ou supérieur) permet de collecter directement ces valeurs sous EXCEL pour faciliter leur analyse
Livré avec
• 1 Mallette
• Une pédale à pied pour la mise à zéro au démarrage du test en gardant les 2 mains libres
• 10 pointes de mesure jetables de 0,5 mm de diamètre
• Une pointe ressort pour seuils de 0-10 grammes
• En option : le « bouton patient » pour un usage chez l’Homme. Cliquez ici pour en savoir plus!Nouveau système AlgoKit
AlgoKit
UN ENSEMBLE COMPLET POUR REPONDRE
A TOUTES LES SITUATIONS DE MESURE DE LA DOULEUR CHEZ LES RONGEURS:
SONDES MULTIPLES, BOÎTIER DE CONTRÔLE ET LOGICIEL UNIQUES
A TOUTES LES SITUATIONS DE MESURE DE LA DOULEUR CHEZ LES RONGEURS:
SONDES MULTIPLES, BOÎTIER DE CONTRÔLE ET LOGICIEL UNIQUES
Vous pouvez également être intéressé par notre nouveau système ALGOKIT afin d'étendre le champs des possibles pour vos recherches. Pour répondre aux diverses demandes concernant les différents cas possibles en mesure de la douleur et pour faire face à toutes les situations, Bioseb est fière de présenter l'AlgoKit construit autour de notre test d'Incapacitance Statique (SWB: Distribution Pondérale Statique), avec son écran tactile couleurs, et de jusqu'à 3 capteurs additionnels parmi notreVon Frey Électronique, de la Pince Instrumentée et de l'algomètre pour petits animaux (SMALGO) combinés à un unique boitier de contrôle ! .
Avantages:
• Flexibilité : solution complète pour les mesure d’analgésie à portée de main !
• Compatible avec le logiciel d'acquisition BIO-CIS2 pour améliorer la répétabilité des tests nociceptifs.
BIO-EVF-WRS
Fiche technique
- Mémoire interne
- jusqu'à 100 valeurs
- Alimentation
- secteur 220-240V (autres voltages sur demande)
- Plage
- 0-500 grammes (5N)
- Résolution
- 0.1 gramme
- Applications
- Arthrite & Arthrose
Cognitive performance
Douleur
Fonctions de motricité générale
Métabolisme
Neurodégénérescence
Système Nerveux Central (SNC)
Système sensoriel
Thématiques transversales
Troubles de l'humeur - Précision
- +/-0.25% de la plein échelle ( +/- 1,25g)
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[title] => Purine nucleoside phosphorylase inhibition is an effective approach for the treatment of chemical hemorrhagic cystitis
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[title] => Nanoporous graphene-based thin-film microelectrodes for in vivo high-resolution neural recording and stimulation
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[title] => CREB1 Facilitates GABAergic Neural Differentiation of Human Mesenchymal Stem Cells through BRN2 for Pain Alleviation and Locomotion Recovery after Spinal Cord Injury
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[title] => Exploring Serum Biomarkers for Neuropathic Pain in Rat Models of Chemotherapy-Induced Peripheral Neuropathy- A Comparative Pilot Study with Oxaliplatin- Paclitaxel- Bortezomib- and Vincristine
[paragraph_crop] => Exploring Serum Biomarkers for Neuropathic Pain in Rat Models of Chemotherapy-Induced [...]
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[title] => Description of Novel Molecular Factors in Lumbar DRGs and Spinal Cord Factors Underlying Development of Neuropathic Pain Component in the Animal Model of Osteoarthritis
[paragraph_crop] => Description of Novel Molecular Factors in Lumbar DRGs and Spinal Cord Factors Underlying [...]
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[title] => Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain
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[title] => Descending serotonergic modulation from rostral ventromedial medulla to spinal trigeminal nucleus is involved in experimental occlusal interference-induced chronic orofacial hyperalgesia
[paragraph_crop] => Descending serotonergic modulation from rostral ventromedial medulla to spinal trigeminal [...]
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[title] => Injectable hypoxia-preconditioned cartilage progenitor cells-laden GelMA microspheres system for enhanced osteoarthritis treatment
[paragraph_crop] => Injectable hypoxia-preconditioned cartilage progenitor cells-laden GelMA microspheres system [...]
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[date] => 2023-04-17 00:00:00
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[title] => Minimally Invasive Periarticular Injections Of Local Anesthetic Provides Prolonged Analgesia In A Rodent Osteoarthritis Model
[paragraph_crop] => Minimally Invasive Periarticular Injections Of Local Anesthetic Provides Prolonged Analgesia [...]
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[title] => Shenqisherong pill ameliorates neuronal apoptosis by inhibiting the JNK and caspase-3 signaling pathway in a rat model of cervical cord compres
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[title] => Enhanced pain facilitation rather than impaired pain inhibition in burning mouth syndrome female patients
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[title] => Targeting TRPV1 activity via high‐dose capsaicin in patients with sickle cell disease
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[date] => 2022-06-27 00:00:00
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[title] => RvD1 disrupts nociceptor neuron and macrophage activation and neuroimmune communication- reducing pain and inflammation in gouty arthritis in mice
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[date] => 2022-06-18 00:00:00
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[title] => Sciatic nerve stimulation alleviates acute neuropathic pain via modulation of neuroinflammation and descending pain inhibition in a rodent model
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[date] => 2022-06-15 00:00:00
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[title] => The Overexpression of Insulin-Like Growth Factor-1 and Neurotrophin-3 Promote Functional Recovery and Alleviate Spasticity After Spinal Cord Injury
[paragraph_crop] => The Overexpression of Insulin-Like Growth Factor-1 and Neurotrophin-3 Promote Functional [...]
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[date] => 2022-04-29 00:00:00
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[title] => Early life pain experience changes adult functional pain connectivity in the rat somatosensory and the medial prefrontal cortex
[paragraph_crop] => Early life pain experience changes adult functional pain connectivity in the rat somatosensory [...]
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[date] => 2022-03-04 00:00:00
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[title] => Painful Diabetic Neuropathy Is Associated with Compromised Microglial IGF-1 Signaling Which Can Be Rescued by Green Tea Polyphenol EGCG in Mice
[paragraph_crop] => Painful Diabetic Neuropathy Is Associated with Compromised Microglial IGF-1 Signaling Which [...]
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[date] => 2022-02-22 00:00:00
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[title] => The Therapeutic Effect of iMSC-Derived Small Extracellular Vesicles on Tendinopathy Related Pain Through Alleviating Inflammation- An in vivo and in vitro Study
[paragraph_crop] => The Therapeutic Effect of iMSC-Derived Small Extracellular Vesicles on Tendinopathy Related [...]
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[title] => proBDNF/p75NTR promotes rheumatoid arthritis and inflammatory response by activating proinflammatory cytokines
[paragraph_crop] => proBDNF/p75NTR promotes rheumatoid arthritis and inflammatory response by activating proinflammatory
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[title] => Alpha-Conotoxin RgIA and oligoarginine R8 in the mice model alleviate long-term oxaliplatin induced neuropathy
[paragraph_crop] => Alpha-Conotoxin RgIA and oligoarginine R8 in the mice model alleviate long-term oxaliplatin [...]
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[title] => Small Extracellular Vesicles Derived From Human Ipsc-Derived MSC Ameliorate Tendinopathy-Related Acute Pain Through Inhibiting Mast Cells Activation
[paragraph_crop] => Small Extracellular Vesicles Derived From Human Ipsc-Derived MSC Ameliorate [...]
[image_presente] =>
[date] => 2021-12-06 00:00:00
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[title] => Involvement of the BDNFÐTrkBÐKCC2 pathway in neuropathic pain after brachial plexus avulsion
[paragraph_crop] => Involvement of the BDNFÐTrkBÐKCC2 pathway in neuropathic pain after brachial plexus avulsion
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[date] => 2021-11-21 00:00:00
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[url] => https://bioseb.com/fr/news/wntbeta-catenin-pathway-in-experimental-model-of-fibromyalgia-role-of-hidrox-n1479
[title] => Wnt/beta-Catenin Pathway in Experimental Model of Fibromyalgia: Role of Hidrox
[paragraph_crop] => Wnt/beta-Catenin Pathway in Experimental Model of Fibromyalgia: Role of Hidrox
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[date] => 2021-11-13 00:00:00
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[title] => Contribution of Trem2 Signaling to the Development of Painful Diabetic Neuropathy by Mediating Microglial Polarization in Mice
[paragraph_crop] => Contribution of Trem2 Signaling to the Development of Painful Diabetic Neuropathy by Mediating [...]
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[date] => 2021-10-26 00:00:00
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[title] => Reversing the surface charge of MSC-derived small extracellular vesicles by epsilonPL-PEG-DSPE for enhanced osteoarthritis treatment
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[title] => Phenotypic Characterization of the Endocannabinoid-Degrading Enzyme Alpha and Beta-Hydrolase Domain 6 Knockout Rat
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[title] => Behavioral phenotyping of cancer pain in domesticated cats with naturally occurring squamous cell carcinoma of the tongue- initial validation studies provide evidence for regional and widespread algoplasticity
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[title] => Genistein reverses the effect of 17beta_estradiol on exacerbating experimental occlusal interference_induced chronic masseter hyperalgesia in ovariectomized rats
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[title] => Astrocytes in the rostral ventromedial medulla contribute to the maintenance of orofacial hyperalgesia induced by late removal of dental occlusal interference
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[title] => Ferroptosis is involved in the development of neuropathic pain and allodynia
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[date] => 2021-04-17 00:00:00
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[title] => Oral supplementation with fish cartilage hydrolysate accelerates joint function recovery in rat model of traumatic knee osteoarthritis
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[title] => Extracellular vesicles released from hiPSC-derived MSCs attenuate chronic prostatitis and chronic pelvic pain syndrome in rats by immunoregulation
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[title] => Preemptive Stem Cells Ameliorate Neuropathic Pain in Rats- A Central Component of Preemptive Analgesia
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[title] => Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker
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[title] => Anti-Inflammatory and Analgesic Effects of TRPV1 Polypeptide Modulator APHC3 in Models of Osteo-and Rheumatoid Arthritis
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[title] => Inhibiting cough by silencing large pore-expressing airway sensory neurons with a charged sodium channel blocker 2
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[date] => 2020-12-07 00:00:00
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[title] => The adjuvant-induced rat model of monoarthritis- welfare implications and possible refinement strategies
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[title] => Albiflorin Attenuates Mood Disorders Under Neuropathic Pain State By Suppressing The Hippocampal NLRP3 Inflammasome Activation During Chronic Constriction Injury
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[title] => Repeated Intrathecal Administration of Ropivacaine Hydrochloride Induces Apoptosis Via Up-Regulating of Fas and FasL Expression in the Rat Spinal Cord
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[title] => Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of AlzheimerÕs disease
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[title] => Alterations of distributed neuronal network oscillations during acute pain in freely-moving mice
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[date] => 2020-08-11 00:00:00
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[title] => Ultrafast ultrasound imaging pattern analysis reveals distinctive dynamic brain states and potent sub-network alterations in arthritic animals
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[title] => The effect of pirfenidone on rat chronic prostatitis and chronic pelvic pain syndrome and its mechanisms
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[title] => The Role of Cashew -Anacardium occidentale L-- Nuts on an Experimental Model of Painful Degenerative Joint Disease
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[title] => Analgesic and Neuroprotective Effects of Electroacupuncture in a Dental Pulp Injury Model
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[title] => NeuroHeal Treatment Alleviates Neuropathic Pain and Enhances Sensory Axon Regeneration
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[title] => Effect of Artesunate on Leishmania Amazonesis Induced Neuroinflammation and Nociceptive Behavior in Male Balb and C Mice
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[title] => Dim light at night exposure induces cold hyperalgesia and mechanical allodynia in male mice
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[title] => GABAergic modulation of secondary hyperalgesia- A randomized controlled 4_way crossover trial with the alpha2_subunit preferring GABA positive allosteric modulator- N_desmethyl_clobazam in healthy volunteers
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[title] => Perioperative intravenous low_dose ketamine for neuropathic pain after major lower back surgery- A randomized- placebo_controlled study
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[title] => Highly bioavailable curcumin powder suppresses articular cartilage damage in rats with mono-iodoacetate -MIA--induced osteoarthritis
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[title] => Minocycline attenuates the development of diabetic neuropathy by modulating DREAM and BDNF protein expression in rat spinal cord
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[title] => IPSE- a parasite-derived host immunomodulatory protein- is a potential therapeutic for hemorrhagic cystitis
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[title] => Cholesterol Depletion Regulates Axonal Growth and Enhances Central and Peripheral Nerve Regeneration
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[title] => Bexarotent attenuated CCI-induced spinal neuroinflammation and neuropathic pain by targeting MKP-1
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[title] => Increased Nociceptive Responses in Streptozotocin-Induced Diabetic Rats and the Related Expression of Spinal NR2B Subunit of N-methyl-D-aspartate Receptors
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[title] => May a sigma_1 antagonist improve neuropathic signs induced by cisplatin and vincristine in rats?
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[title] => Hydrogen-Rich Saline Activated Autophagy via HIF-1_ Pathways in Neuropathic Pain Model
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[title] => On the use of Parylene C polymer as substrate for peripheral nerve electrodes
[paragraph_crop] => On the use of Parylene C polymer as substrate for peripheral nerve electrodes
[image_presente] =>
[date] => 2018-04-13 00:00:00
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[title] => Transdermal Fentanyl Solution Provides Long-term Analgesia in the Hind-paw Incisional Model of Postoperative Pain in Male Rats
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[title] => Role of medullary astroglial glutamine synthesis in tooth pulp hypersensitivity associated with frequent masseter muscle contraction
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[title] => Schwann cells and mesenchymal stem cells in laminin- or fibronectin-aligned matrices and regeneration across a critical size defect of 15 mm in the rat sciatic nerve
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[title] => Monoaminergic descending pathways contribute to modulation of neuropathic pain by increasing-intensity treadmill exercise after peripheral nerve injury
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[title] => Time course study of long-term biocompatibility and foreign body reaction to intraneural polyimide-based implants
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[title] => CXCR4 signaling contributes to alveolar bone resorption in Porphyromonas gingivalis-induced periodontitis in mice
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[title] => Group I metabotropic glutamate receptor plasticity after peripheral inflammation alters nociceptive transmission in the dorsal horn of the spinal cord in adult rats
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[title] => Antinociceptive- antiallodynic and antihyperalgesic effects of the 5-HT1A receptor selective agonist- NLX-112 in mouse models of pain
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[title] => 5_HT in the dorsal raphe nucleus is involved in the effects of 100_Hz electro_acupuncture on the pain_depression dyad in rats
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[title] => Cav1- 2 and Cav1- 3 l‐type calcium channels independently control short‐and long‐term sensitization to pain
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[title] => Inhibition of the neuronal NFκB pathway attenuates bortezomib-induced neuropathy in a mouse model-
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[title] => Effect of dexmedetomidine and cold stress in a rat model of neuropathic pain- Role of interleukin-6 and tumor necrosis factor-α
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[title] => In vitro and non?invasive in vivo effects of the cannabinoid?1 receptor agonist AM841 on gastrointestinal motor function in the rat
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[title] => Early increasing-intensity treadmill exercise reduces neuropathic pain by preventing nociceptor collateral sprouting and disruption of chloride cotransporters homeostasis after peripheral nerve injury
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[image_presente] =>
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[title] => 3-[4--3-Trifluoromethyl-phenyl--piperazin-1-yl]-dihydrofuran-2-one and pregabalin attenuate tactile allodynia in the mouse model of chronic constriction injury
[paragraph_crop] => 3-[4--3-Trifluoromethyl-phenyl--piperazin-1-yl]-dihydrofuran-2-one and pregabalin attenuate tactile
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[title] => Changes of voltage-gated sodium channels in sensory nerve regeneration and neuropathic pain models
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[image_presente] =>
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[url] => https://bioseb.com/fr/news/inflammatory-pain-memory-facilitates-occlusal-interferenceinduced-masticatory-muscle-hyperalgesia-in-rats-n774
[title] => Inflammatory pain memory facilitates occlusal interference?induced masticatory muscle hyperalgesia in rats
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[image_presente] =>
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[title] => NKCC1 Activation Is Required for Myelinated Sensory Neurons Regeneration through JNK-Dependent Pathway
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[image_presente] =>
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[url] => https://bioseb.com/fr/news/biocompatibility-evaluation-of-parylene-c-and-polyimide-as-substrates-for-peripheral-nerve-interfaces-n765
[title] => Biocompatibility evaluation of parylene C and polyimide as substrates for peripheral nerve interfaces
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[image_presente] =>
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[title] => GABAergic modulation in central sensitization in humans- a randomized placebo-controlled pharmacokinetic-pharmacodynamic study comparing clobazam with clonazepam in healthy volunteers-
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[title] => Antinociceptive activity of transient receptor potential channel TRPV1- TRPA1- and TRPM8 antagonists in neurogenic and neuropathic pain models in mice
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[title] => Effects of Electroacupuncture with Dominant Frequency at SP 6 and ST 36 Based on Meridian Theory on Pain-depression Dyad in Rats
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[title] => A three-dimensional self-opening intraneural peripheral interface -SELINE-
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[image_presente] =>
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[title] => Involvement of TRPV1 and TRPA1 in Incisional Intraoral and Extraoral Pain
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[title] => Nociceptive spinal cord neurons of laminae I-III exhibit oxidative stress damage during diabetic neuropathy which is prevented by early antioxidant treatment with epigallocatechin-gallate -EGCG-
[paragraph_crop] => Nociceptive spinal cord neurons of laminae I-III exhibit oxidative stress damage during [...]
[image_presente] =>
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[url] => https://bioseb.com/fr/news/tubulization-with-chitosan-guides-for-the-repair-of-long-gap-peripheral-nerve-injury-in-the-rat-n674
[title] => Tubulization with chitosan guides for the repair of long gap peripheral nerve injury in the rat
[paragraph_crop] => Tubulization with chitosan guides for the repair of long gap peripheral nerve injury in the rat
[image_presente] =>
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[title] => BDNF-dependent plasticity induced by peripheral inflammation in the primary sensory and the cingulate cortex triggers cold allodynia and reveals a major role for endogenous BDNF as a tuner of the affective aspect of pain
[paragraph_crop] => BDNF-dependent plasticity induced by peripheral inflammation in the primary sensory and the [...]
[image_presente] =>
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[url] => https://bioseb.com/fr/news/analgesic-effects-of-clinically-used-compounds-in-novel-mouse-models-of-polyneuropathy-induced-by-oxaliplatin-and-cisplatin-n629
[title] => Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin
[paragraph_crop] => Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced [...]
[image_presente] =>
[date] => 2014-10-16 00:00:00
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[url] => https://bioseb.com/fr/news/buccal-acetaminophen-provides-fast-analgesia--two-randomized-clinical-trials-in-healthy-volunteers-n697
[title] => Buccal acetaminophen provides fast analgesia- two randomized clinical trials in healthy volunteers
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[image_presente] =>
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[title] => Monoarthritis-induced emotional and cognitive impairments in rats are sensitive to low systemic doses or intra-amygdala injections of morphine
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[title] => Face-to-face comparison of the predictive validity of two models of neuropathic pain in the rat- Analgesic activity of pregabalin- tramadol and duloxetine
[paragraph_crop] => Face-to-face comparison of the predictive validity of two models of neuropathic pain in the [...]
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[title] => Antiallodynic and antihyperalgesic activity of 3-[4--3-trifluoromethyl-phenyl--piperazin-1-yl]-dihydrofuran-2-one compared to pregabalin in chemotherapy-induced neuropathic pain in mice
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[title] => Bone marrow mesenchymal stromal cells and olfactory ensheathing cells transplantation after spinal cord injury – a morphological and functional comparison in rats
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[title] => Molecular Mechanisms Underlying the Enhanced Analgesic Effect of Oxycodone Compared to Morphine in Chemotherapy-Induced Neuropathic Pain
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[title] => Assessment of sensory thresholds and nociceptive fiber growth after sciatic nerve injury reveals the differential contribution of collateral reinnervation and nerve regeneration to neuropathic pain
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[title] => A Polyamine-Deficient Diet Prevents Oxaliplatin-Induced Acute Cold and Mechanical Hypersensitivity in Rats
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[title] => Structural and Molecular Alterations of Primary Afferent Fibres in the Spinal Dorsal Horn in Vincristine-Induced Neuropathy in Rat
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[title] => Phagocytic microglial phenotype induced by glibenclamide improves functional recovery but worsens hyperalgesia after spinal cord injury in adult rats
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[title] => An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1-6 in peripheral pain pathways
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[title] => Local and remote immune-mediated inflammation after mild peripheral nerve compression in rats-
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[image_presente] =>
[date] => 2013-07-31 00:00:00
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[title] => Unexpected association of the “inhibitory” neuroligin 2 with excitatory PSD95 in neuropathic pain
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[title] => Bilateral lesions of the nigrostriatal pathways are associated with chronic mechanical pain hypersensitivity in rats
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[date] => 2013-05-15 00:00:00
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[title] => Plastic changes in lumbar segments after thoracic spinal cord injuries in adult rats- An integrative view of spinal nociceptive dysfunctions
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[title] => Characterization of cannabinoid-induced relief of neuropathic pain in a rat model of cisplatin-induced neuropathy
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[title] => Acute delivery of EphA4-Fc improves functional recovery after contusive spinal cord injury in rats
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[title] => Differential effects of activity dependent treatments on axonal regeneration and neuropathic pain after peripheral nerve injury
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[title] => Metabotropic glutamate receptor 5 contributes to inflammatory tongue pain via extracellular signalregulated kinase signaling in the trigeminal spinal subnucleus caudalis and upper cervical spinal cord
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[title] => Hydrogen-rich saline activated autophagy via HIF-1α pathways in neuropathic pain model
[paragraph_crop] => Hydrogen-rich saline activated autophagy via HIF-1α pathways in neuropathic pain model
[image_presente] =>
[date] => 2012-10-26 00:00:00
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[title] => Validation of the simplified UVB model to assess the pharmacodynamics of analgesics in healthy human volunteers
[paragraph_crop] => Validation of the simplified UVB model to assess the pharmacodynamics of analgesics in healthy [...]
[image_presente] =>
[date] => 2012-05-05 00:00:00
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[title] => A Randomized- Controlled Trial Validates a Peripheral Supra-Additive Antihyperalgesic Effect of a Paracetamol–Ketorolac Combination-
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[url] => https://bioseb.com/fr/news/characteristics-of-the-neuropathy-induced-by-thoracotomy--a-4-month-follow-up-study-with-psychophysical-examination-n1366
[title] => Characteristics of the neuropathy induced by thoracotomy- a 4 month follow-up study with psychophysical examination
[paragraph_crop] => Characteristics of the neuropathy induced by thoracotomy- a 4 month follow-up study with [...]
[image_presente] =>
[date] => 2011-08-01 00:00:00
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[title] => Bidirectional integrative regulation of Cav1-2 calcium channel by microRNA miR-103- role in pain-
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[image_presente] =>
[date] => 2011-07-29 00:00:00
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[title] => Intrinsic membrane properties of spinal dorsal horn neurones modulate nociceptive information processing in vivo-
[paragraph_crop] => Intrinsic membrane properties of spinal dorsal horn neurones modulate nociceptive information [...]
[image_presente] =>
[date] => 2011-06-01 00:00:00
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[title] => Biocompatibility of Chronically Implanted Transverse Intrafascicular Multichannel Electrode -TIME- in the Rat Sciatic Nerve-
[paragraph_crop] => Biocompatibility of Chronically Implanted Transverse Intrafascicular Multichannel Electrode [...]
[image_presente] =>
[date] => 2011-05-12 00:00:00
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[title] => Passive and active exercise improve regeneration and muscle reinnervation after peripheral nerve injury in the rat-
[paragraph_crop] => Passive and active exercise improve regeneration and muscle reinnervation after peripheral [...]
[image_presente] =>
[date] => 2011-04-08 00:00:00
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[url] => https://bioseb.com/fr/news/longitudinal-study-of-wind-up-responses-after-graded-spinal-cord-injuries-in-the-adult-rat---n294
[title] => Longitudinal study of wind-up responses after graded spinal cord injuries in the adult rat-
[paragraph_crop] => Longitudinal study of wind-up responses after graded spinal cord injuries in the adult rat.
[image_presente] =>
[date] => 2011-02-01 00:00:00
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[title] => Analgesic properties of calcium phosphate apatite loaded with bupivacaine on postoperative pain-
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[image_presente] =>
[date] => 2010-07-30 00:00:00
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[title] => Knockdown of L Calcium Channel Subtypes- Differential Effects in Neuropathic Pain-
[paragraph_crop] => Knockdown of L Calcium Channel Subtypes: Differential Effects in Neuropathic Pain.
[image_presente] =>
[date] => 2010-01-20 00:00:00
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[title] => Electrical stimulation combined with exercise increase axonal regeneration after peripheral nerve injury-
[paragraph_crop] => Electrical stimulation combined with exercise increase axonal regeneration after peripheral [...]
[image_presente] =>
[date] => 2009-09-01 00:00:00
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[url] => https://bioseb.com/fr/news/nociceptive-responses-and-spinal-plastic-changes-of-afferent-c-fibers-in-three-neuropathic-pain-models-induced-by-sciatic-nerve-injury-in-the-rat--n220
[title] => Nociceptive responses and spinal plastic changes of afferent C-fibers in three neuropathic pain models induced by sciatic nerve injury in the rat-
[paragraph_crop] => Nociceptive responses and spinal plastic changes of afferent C-fibers in three neuropathic [...]
[image_presente] =>
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[title] => Antinociceptive and anti-allodynic effects of oral PL37- a complete inhibitor of enkephalin-catabolizing enzymes- in a rat model of peripheral neuropathic pain induced by vincristine-
[paragraph_crop] => Antinociceptive and anti-allodynic effects of oral PL37, a complete inhibitor of [...]
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[date] => 2008-12-14 00:00:00
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[title] => Perception du chaud et du froid
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[url] => https://bioseb.com/fr/news/motor-cortex-rtms-in-chronic-neuropathic-pain--pain-relief-is-associated-with-thermal-sensory-perception-improvement--n134
[title] => Motor cortex rTMS in chronic neuropathic pain- pain relief is associated with thermal sensory perception improvement-
[paragraph_crop] => Motor cortex rTMS in chronic neuropathic pain: pain relief is associated with thermal sensory [...]
[image_presente] =>
[date] => 2008-09-01 00:00:00
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[url] => https://bioseb.com/fr/news/acetaminophen-reinforces-descending-inhibitory-pain-pathways--n167
[title] => Acetaminophen Reinforces Descending Inhibitory Pain Pathways-
[paragraph_crop] => Acetaminophen Reinforces Descending Inhibitory Pain Pathways.
[image_presente] =>
[date] => 2008-07-30 00:00:00
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[id] => 159
[url] => https://bioseb.com/fr/news/immediate-electrical-stimulation-enhances-regeneration-and-reinnervation-and-modulates-spinal-plastic-changes-after-sciatic-nerve-injury-and-repair--n159
[title] => Immediate electrical stimulation enhances regeneration and reinnervation and modulates spinal plastic changes after sciatic nerve injury and repair-
[paragraph_crop] => Immediate electrical stimulation enhances regeneration and reinnervation and modulates spinal [...]
[image_presente] =>
[date] => 2008-05-30 00:00:00
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[url] => https://bioseb.com/fr/news/cutaneous-amitriptyline-in-human-volunteers--differential-effects-on-the-components-of-sensory-information-n1368
[title] => Cutaneous Amitriptyline in Human Volunteers- Differential Effects on the Components of Sensory Information
[paragraph_crop] => Cutaneous Amitriptyline in Human Volunteers- Differential Effects on the Components of Sensory [...]
[image_presente] =>
[date] => 2008-04-01 00:00:00
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[76] => Array
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[id] => 76
[url] => https://bioseb.com/fr/news/hyperalgesia-induced-by-cutaneous-freeze-injury-for-testing-analgesics-in-healthy-volunteers--n76
[title] => Hyperalgesia induced by cutaneous freeze injury for testing analgesics in healthy volunteers-
[paragraph_crop] => Hyperalgesia induced by cutaneous freeze injury for testing analgesics in healthy volunteers.
[image_presente] =>
[date] => 2006-04-30 00:00:00
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[58] => Array
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[url] => https://bioseb.com/fr/news/the-novel-analgesic--f-13640--produces-intra--and-postoperative-analgesia-in-a-rat-model-of-surgical-pain--n58
[title] => The novel analgesic- F 13640- produces intra- and postoperative analgesia in a rat model of surgical pain-
[paragraph_crop] => The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of [...]
[image_presente] =>
[date] => 2005-10-31 00:00:00
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[title] => Publications
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[20] => Array
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[id] => 20
[url] => https://bioseb.com/fr/news/up-regulation-of-fatty-acid-metabolizing-enzymes-mrna-in-rat-spinal-cord-during-persistent-peripheral-local-inflammation--n20
[title] => Up-regulation of fatty acid metabolizing-enzymes mRNA in rat spinal cord during persistent peripheral local inflammation-
[paragraph_crop] => Up-regulation of fatty acid metabolizing-enzymes mRNA in rat spinal cord during persistent [...]
[image_presente] =>
[date] => 2003-10-30 00:00:00
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[9] => Array
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[url] => https://bioseb.com/fr/news/large-amplitude-5-ht1a-receptor-activation--a-new-mechanism-of-profound--central-analgesia--n9
[title] => Large-amplitude 5-HT1A receptor activation- a new mechanism of profound- central analgesia-
[paragraph_crop] => Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.
[image_presente] =>
[date] => 2002-11-30 00:00:00
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[10] => Array
(
[id_prestablog_categorie] => 10
[title] => Douleur
[link_rewrite] => Douleur
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[27] => Array
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[id_prestablog_categorie] => 27
[title] => Douleurs générales
[link_rewrite] => Douleurs-generales
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[29] => Array
(
[id_prestablog_categorie] => 29
[title] => Douleurs neuropathiques
[link_rewrite] => Douleurs-neuropathiques
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[95] => Array
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[id_prestablog_categorie] => 95
[title] => Pharmacologie
[link_rewrite] => Pharmacologie
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
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[24] => Array
(
[id_prestablog_categorie] => 24
[title] => Thématiques transversales
[link_rewrite] => Thematiques-transversales
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)
1Nombre de publications:
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Von Frey Électronique - Sans Fil
Bioseb - Bouton Patient EVF BIOSEB-EVF-2023
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