Cold Hot Plate Test

Presentation

Bioseb’s Cold and Hot Plate Test is an innovative instrument opening new investigation fields for your analgesia research by allowing you to test animal's sensitivity to pain resulting from exposure to heat or cold.

This innovative Analgesia Meter is based on a metal plate which can be heated to 55°C and cooled to -2°C (with an ambient temperature between 20°C and 25°C). An electronic thermostat maintains the plate's temperature and a front panel digital thermometer displays the current plate temperature.

The Bioseb Cold and Hot Plate is designed to be very simple to use and very fast to reach the set temperature (as example From ambient to 4°C, the most used threshold value, it takes less than 10 minutes, and from 4°C to 55°C it takes only 5 minutes). Metrology wise, is accurate to less than 0,5°C (EEC metrology standard) and perfectly constant in the animal holder system. The preset temperature will not change for more than 0,1°C when a 400g rat is placed on the plate, and return to the set temperature is almost immediate.

Operation Principle

The animal's pain sensitivity resulting from exposure to heat or cold is tested by placing the animal (mouse or rat) on the surface of the plate and starting a built-in timer. The operator stops the timer at the instant the animal lifts its paw from the plate, reacting to the discomfort. The front panel timer then displays the number of seconds it took the animal to react. Animal reaction time is a measurement of animal resistance to pain and is used to measure efficacy of analgesics.

The operator can start and stop the timer with the front panel start/stop switch or with the included footswitch, which allows 'hands-free' operation.