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Kits contextuels pour T2CT - Double aversion & CPP
Les Kits contextuels pour T2CT ont été conçus pour enrichir les études de préférence de place...
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Évitement passif
Référence : LE870
Catégorie : Apprentissage/Mémoire - Attention - Addiction
Test de motivation par la peur, classiquement utilisé
pour évaluer la mémoire à long ou court terme
sur de petits animaux de laboratoire
pour évaluer la mémoire à long ou court terme
sur de petits animaux de laboratoire
PrésentationL'inhibition de comportements innés ou acquis par association avec une stimulation aversive s'est révélée être un outil très utile pour de nombreux chercheurs travaillant dans différents domaines. De l'étude des interférences de traitements pharmacologiques sur un modèle d'apprentissage simple à l'étude de mécanismes physiologiques sous-jacents à l'apprentissage et à la mémoire, le réflexe d'évitement passif peut être utilisé dans un large spectre d'expériences.
Beaucoup de modèles ont été proposés pour ces études. Cependant, parmi ceux les plus usités, celui suggéré par Kurtz & Pearl en 1960 (J. Comp Physiol. Phycol. 53:201-6) et modifié plus tard par Bures & Buresova (J. Comp. Physiol. Phycol. 56:268-62, 1963) est un des plus éprouvés. Dans ce modèle, parfois appelé 'apprentissage en un essai', 'test à double compartiment' ou 'test de mémoire', on tente d'inhiber, par stimulation aversive, la tendance naturelle des rongeurs à abandonner les espaces larges et illuminés pour se cacher dans les espaces confinés et sombres.
Principe de fonctionnementCe modèle a défini un certain nombre de variables faciles à déterminer et à contrôler (comme le temps de latence avant entrée dans le petit compartiment sombre), et offert en même temps un large spectre de paramètres dont les effets peuvent être étudiés (comme l’intervalle entre les stimulations aversives et le test de rétention).
Les études d'évitement passif sont conduites dans un compartiment expérimental comprenant deux zones de tailles différentes, une grande zone blanche et une petite zone noire, selon le dessin original.
Système complet d'évitement passif avec LE2708 Programmateur avec stimulateur
Dans ce modèle, la position de l'animal est détectée au moyen de capteurs de poids. Ce système, qui utilise des capteurs à haute sensibilité sur une plage de 10 à 800 grammes, permet une détection plus efficace et fiable de la réponse animale (entrées de zone) que les systèmes basés sur des cellules photoélectriques ou des grilles de déplacement au sol.
OptionsLes boîtes du test d’évitement passif de BIOSEB peuvent être contrôlées soit par le biais du programmateur avec stimulateur LE2708 ou d’un logiciel SHUTAVOID.
La première option est recommandée dans le cadre de configurations avec une seule boîte et peut-être combinée avec le logiciel SEDACOM qui se limite au transfert de données du programmateur à un PC via un port RS232. Il n’est pas nécessaire que l’interface ou la carte soient installés sur le PC. Le lien est assuré via un seul câble d’une boîte à l’autre. La première boîte est reliée à un PC ou ordinateur portable par le port RS232 ou USB.
La deuxième option est apte à commander un certain nombre de boîtes en même temps.
Cliquez ici pour télécharger un document PDF comportant des informations détaillées sur le test d'évitement passif
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LE870
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[title] => Publications
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[548] => Array
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[id] => 548
[url] => https://bioseb.com/fr/news/the-g-proteingated-k-channel--ikach--is-required-for-regulation-of-pacemaker-activity-and-recovery-of-resting-heart-rate-after-sympathetic-stimulation--n548
[title] => The G-protein–gated K channel- IKACh- is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation
[paragraph_crop] => The G-protein–gated K+ channel, IKACh, is required for regulation of pacemaker activity and r [...]
[image_presente] =>
[date] => 2013-07-15 00:00:00
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[421] => Array
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[id] => 421
[url] => https://bioseb.com/fr/news/unlike-physical-exercise--modified-environment-increases-the-lifespan-of-sod1g93a-mice-however-both-conditions-induce-cellular-changes-n421
[title] => Unlike Physical Exercise- Modified Environment Increases the Lifespan of SOD1G93A Mice However Both Conditions Induce Cellular Changes
[paragraph_crop] => Unlike Physical Exercise, Modified Environment Increases the Lifespan of SOD1G93A Mice However [...]
[image_presente] =>
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[title] => Sclérose Latérale Amyotrophique (SLA), ou Maladie de Charcot
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[url] => https://bioseb.com/fr/news/different-timing-of-changes-in-mitochondrial-functions-following-endurance-training---n383
[title] => Different Timing of Changes in Mitochondrial Functions following Endurance Training-
[paragraph_crop] => Different Timing of Changes in Mitochondrial Functions following Endurance Training.
[image_presente] =>
[date] => 2012-02-01 00:00:00
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[url] => https://bioseb.com/fr/news/mitochondria-of-trained-skeletal-muscle-are-protected-from-deleterious-effects-of-statins--n364
[title] => Mitochondria of trained skeletal muscle are protected from deleterious effects of statins-
[paragraph_crop] => Mitochondria of trained skeletal muscle are protected from deleterious effects of statins.
[image_presente] =>
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[title] => Métabolisme
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[title] => Métabolisme général
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[title] => Système musculaire
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[351] => Array
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[id] => 351
[url] => https://bioseb.com/fr/news/kinematics-of-obstacle-clearance-in-the-rat---n351
[title] => Kinematics of obstacle clearance in the rat-
[paragraph_crop] => Kinematics of obstacle clearance in the rat.
[image_presente] =>
[date] => 2011-10-31 00:00:00
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[title] => Locomotion
[link_rewrite] => Locomotion
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[id_prestablog_categorie] => 2
[title] => Publications
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[14] => Array
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[title] => Système moteur
[link_rewrite] => Systeme-moteur
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[342] => Array
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[id] => 342
[url] => https://bioseb.com/fr/news/e2f-transcription-factor-1-regulates-oxidative-metabolism---n342
[title] => E2F transcription factor-1 regulates oxidative metabolism-
[paragraph_crop] => E2F transcription factor-1 regulates oxidative metabolism.
[image_presente] =>
[date] => 2011-08-14 00:00:00
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[title] => Métabolisme
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[title] => Métabolisme cellulaire
[link_rewrite] => Metabolisme-cellulaire
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[id_prestablog_categorie] => 2
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[274] => Array
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[id] => 274
[url] => https://bioseb.com/fr/news/predicting-sensorimotor-and-memory-deficits-after-neonatal-ischemic-stroke-with-reperfusion-in-the-rat---n274
[title] => Predicting sensorimotor and memory deficits after neonatal ischemic stroke with reperfusion in the rat-
[paragraph_crop] => Predicting sensorimotor and memory deficits after neonatal ischemic stroke with reperfusion in [...]
[image_presente] =>
[date] => 2010-09-01 00:00:00
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[title] => Domaines de recherche divers
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[url] => https://bioseb.com/fr/news/immediate-and-delayed-life-history-effects-caused-by-food-deprivation-early-in-life-in-a-short-lived-lizard--n275
[title] => Immediate and delayed life history effects caused by food deprivation early in life in a short-lived lizard-
[paragraph_crop] => Immediate and delayed life history effects caused by food deprivation early in life in a [...]
[image_presente] =>
[date] => 2010-09-01 00:00:00
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[title] => Autres animaux
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[title] => Métabolisme
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[title] => Prise alimentaire / Nutrition
[link_rewrite] => Prise-alimentaire-Nutrition
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[title] => Publications
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[title] => Thematiques diverses
[link_rewrite] => Thematiques-diverses
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[175] => Array
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[id] => 175
[url] => https://bioseb.com/fr/news/brain-glucagon-like-peptide-1-signaling-controls-the-onset-of-high-fat-diet-induced-insulin-resistance-and-reduces-energy-expenditure--n175
[title] => Brain Glucagon-Like Peptide 1 Signaling Controls the Onset of High-Fat Diet-Induced Insulin Resistance and Reduces Energy Expenditure-
[paragraph_crop] => Brain Glucagon-Like Peptide 1 Signaling Controls the Onset of High-Fat Diet-Induced Insulin [...]
[image_presente] =>
[date] => 2008-10-01 00:00:00
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[title] => Diabète, Insuline & Glucose
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[title] => Métabolisme
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[82] => Array
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[title] => Prise alimentaire / Nutrition
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[title] => Publications
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[49] => Array
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[id] => 49
[url] => https://bioseb.com/fr/news/inter--and-intrastrain-variation-in-mouse-critical-running-speed--n49
[title] => Inter- and intrastrain variation in mouse critical running speed-
[paragraph_crop] => Inter- and intrastrain variation in mouse critical running speed.
[image_presente] =>
[date] => 2005-04-01 00:00:00
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[title] => Dépenses énergétiques
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[title] => Métabolisme
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1Nombre de publications:
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