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CONFERENCES & MEETINGS 
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Passive avoidance
Reference : LE870
Category : Learning/Memory - Attention - Addiction
Fear-motivated tests classically used to assess short-term or long-term memory on small laboratory animals
PresentationThe inhibition of innate or learned behaviour by association with aversive stimulation has shown to be a very useful tool for researchers working in very different fields. From the study of the interference of drug treatments on a simple learning model to the study of the physiological mechanisms beneath learning or memory, passive avoidance reflexes studies have been used.
Many models have been proposed for these studies. However, among those most widely used, that suggested by Kurtz & Pearl in 1960 (J. Comp Physiol. Phycol. 53:201-6) and later modified by Bures & Buresova (J. Comp. Physiol. Phycol. 56:268-62, 1963) is proven. In this model, sometimes called ‘One-trial learning’, ‘Two-compartment test’ or ‘Memory test’ it is intended to inhibit, by aversive stimulus, the rodents tendency to abandon large, open and brightly illuminated spaces so as to hide in small dark ones.
Operating principleThe model has a set of variables of easy determination and control (i.e. entrance to the small compartment latency), offering, at the same time, an ample parameters spectrum whose effect can be studied (v. gr. the interval between the aversive stimulation and the retention test).
Passive Avoidance studies can be carried out by means of an experimental chamber that comprised of two differently sized enclosures, a big white one and a small black one, according to the original design.
Passive avoidance complete system with LE2708 Avoidance programmer
In this experimental chamber, the animal’s position is detected by using weight gauges. This system, which uses high sensitivity weight transducers that range from 10 to 800 grams, provides more effective and reliable detection of animal responses (zones entries) than systems based on photocells beams or on grid floor displacements.
OptionsBIOSEB Passive Avoidance boxes may be controlled either through LE2708 Programmer or SHUTAVOID software.
The first option is recommended for one single box set-ups, and may be combined with SEDACOM software - which is limited to enable data transfer from the programmer to a PC through a RS232 port. It is not necessary the interface neither the use of board installed into the PC. The link is carried out by one only cable from one Box to the other. The first Box is connected to PC or Laptop by the port RS 232 or USB.
The second option is suitable for controlling a number of boxes simultaneously.
Click here to download PDF data with detailled information about our Passive Avoidance test
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LE870
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[title] => Early postnatal motor experience shapes the motor properties of C57BL and 6J adult mice-
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[title] => The G-protein–gated K channel- IKACh- is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation
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[title] => Publications
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[url] => https://bioseb.com/en/news/unlike-physical-exercise--modified-environment-increases-the-lifespan-of-sod1g93a-mice-however-both-conditions-induce-cellular-changes-n421
[title] => Unlike Physical Exercise- Modified Environment Increases the Lifespan of SOD1G93A Mice However Both Conditions Induce Cellular Changes
[paragraph_crop] => Unlike Physical Exercise, Modified Environment Increases the Lifespan of SOD1G93A Mice However [...]
[image_presente] =>
[date] => 2012-09-20 00:00:00
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[title] => Amyotrophic Lateral Sclerosis (ALS)
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[title] => Muscular system
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[383] => Array
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[id] => 383
[url] => https://bioseb.com/en/news/different-timing-of-changes-in-mitochondrial-functions-following-endurance-training---n383
[title] => Different Timing of Changes in Mitochondrial Functions following Endurance Training-
[paragraph_crop] => Different Timing of Changes in Mitochondrial Functions following Endurance Training.
[image_presente] =>
[date] => 2012-02-01 00:00:00
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[url] => https://bioseb.com/en/news/mitochondria-of-trained-skeletal-muscle-are-protected-from-deleterious-effects-of-statins--n364
[title] => Mitochondria of trained skeletal muscle are protected from deleterious effects of statins-
[paragraph_crop] => Mitochondria of trained skeletal muscle are protected from deleterious effects of statins.
[image_presente] =>
[date] => 2012-01-13 00:00:00
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[title] => Skeletal functions
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[351] => Array
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[id] => 351
[url] => https://bioseb.com/en/news/kinematics-of-obstacle-clearance-in-the-rat---n351
[title] => Kinematics of obstacle clearance in the rat-
[paragraph_crop] => Kinematics of obstacle clearance in the rat.
[image_presente] =>
[date] => 2011-10-31 00:00:00
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[55] => Array
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[id_prestablog_categorie] => 55
[title] => Locomotion
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[title] => Motor control
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[342] => Array
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[id] => 342
[url] => https://bioseb.com/en/news/e2f-transcription-factor-1-regulates-oxidative-metabolism---n342
[title] => E2F transcription factor-1 regulates oxidative metabolism-
[paragraph_crop] => E2F transcription factor-1 regulates oxidative metabolism.
[image_presente] =>
[date] => 2011-08-14 00:00:00
[categories] => Array
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[78] => Array
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[id_prestablog_categorie] => 78
[title] => Cell metabolism
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[title] => Metabolism
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[274] => Array
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[id] => 274
[url] => https://bioseb.com/en/news/predicting-sensorimotor-and-memory-deficits-after-neonatal-ischemic-stroke-with-reperfusion-in-the-rat---n274
[title] => Predicting sensorimotor and memory deficits after neonatal ischemic stroke with reperfusion in the rat-
[paragraph_crop] => Predicting sensorimotor and memory deficits after neonatal ischemic stroke with reperfusion in [...]
[image_presente] =>
[date] => 2010-09-01 00:00:00
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[url] => https://bioseb.com/en/news/immediate-and-delayed-life-history-effects-caused-by-food-deprivation-early-in-life-in-a-short-lived-lizard--n275
[title] => Immediate and delayed life history effects caused by food deprivation early in life in a short-lived lizard-
[paragraph_crop] => Immediate and delayed life history effects caused by food deprivation early in life in a [...]
[image_presente] =>
[date] => 2010-09-01 00:00:00
[categories] => Array
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[82] => Array
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[id_prestablog_categorie] => 82
[title] => Food intake / Nutrition
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[title] => Metabolism
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[title] => Miscellaneous
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[title] => Other animals
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[175] => Array
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[id] => 175
[url] => https://bioseb.com/en/news/brain-glucagon-like-peptide-1-signaling-controls-the-onset-of-high-fat-diet-induced-insulin-resistance-and-reduces-energy-expenditure--n175
[title] => Brain Glucagon-Like Peptide 1 Signaling Controls the Onset of High-Fat Diet-Induced Insulin Resistance and Reduces Energy Expenditure-
[paragraph_crop] => Brain Glucagon-Like Peptide 1 Signaling Controls the Onset of High-Fat Diet-Induced Insulin [...]
[image_presente] =>
[date] => 2008-10-01 00:00:00
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[81] => Array
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[id_prestablog_categorie] => 81
[title] => Diabetes, Insulin & Glucose
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[title] => Food intake / Nutrition
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[title] => Metabolism
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[title] => Publications
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[49] => Array
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[id] => 49
[url] => https://bioseb.com/en/news/inter--and-intrastrain-variation-in-mouse-critical-running-speed--n49
[title] => Inter- and intrastrain variation in mouse critical running speed-
[paragraph_crop] => Inter- and intrastrain variation in mouse critical running speed.
[image_presente] =>
[date] => 2005-04-01 00:00:00
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[title] => Energy expenditure
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1Number of publications:
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