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CONFERENCES & MEETINGS 
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Rodent pincher - Analgesia meter - Wireless
Reference : BIO-RP-WRS
Category : Pain - Mechanical Allodynia / Hyperalgesia
A fast and accurate algometer based on an instrumented pincher as an alternative to the Randall-Selitto test: This new analgesia meter developed by Bioseb following Luis-Delgado et al. (2005) allows accurate nociceptive tests to measure mechanical pain threshold on rat or mouse limbs with minimal constraint. Now wireless, to be free from annoying cables!
Presentation
Bioseb's 'Rodent Pincher' algometer allows calibrated forceps to induce quantifiable mechanical stimulation in the animal (rats or mice) on a linear scale. The most suitable protocol was experimented by determining the effects of 3 repetitive measurements on the 2 hindpaws, respectively over long-term (9 days), mid-term (1 day) and short-term (2 hours). It was primarily developed as an analgesimeter/algometer (analgesia measurement instrument) for nociceptive tests. In this specific use, the Rodents Pincher not only represents an alternative to the 'RANDALL & SELITTO' test - but also presents the following advantages when compared to the classical test:
• More ethical handling, less stressful for the animal (rat or mouse) resulting in less variable measurements
• Faster measurement, less traumatic for the tissues
• Digital measurement with metrological traceability
Furthermore, this pincher-based analgesia meter can also be used for other applications that require a controlled force or pressures values, for example :
• Sensitivity recovery after nerve crush: pinching is applied at several places over the paw to see the sensitivity recovery
• Mechanical injuries for thrombotic models
• Mechanical stimulation for in vivo electrophysiological recordings using the possibility to trigger recording on force thresholds
Comparative studies (including comparative tests with the Randall & Sellito analgesimeter) have demonstrated the accuracy of this pincher-based algometer for easy, fast and reproducible measurement of mechanical pain threshold on rat limbs. Moreover, it allowed to perform rat analagesia testing with minimal constraint, which reduces data variability.
One of these experimental research works was carried out by the team of Prof. Poisbeau in the 'Nociception & Pain' department of the 'Institut des Neurosciences Cellulaires et Intégratives' (Université Louis pasteur) in Strasbourg.
This work was described in two articles published in December 2005 in international reviews with a controlling committee:
• Validation method :
Calibrated Forceps: A Sensitive and Reliable Tool for Pain and Analgesia Studies, by Luis-Delgado et al. in The Journal of pain, December 2005
• Scientific work :
Inflammatory Pain Upregulates Spinal Inhibition via Endogenous Neurosteroid Production, by P. Poisbeau et al. in The Journal of neuroscience, December 2005
Click on the title of one of the articles to send a request to download the PDF file
Operating principle
The pressure is applied in the 'inter-digital' region. When used on the rat the pressure can also be applied to the tail. The instrument displays the force (in grams, newton, oz, lbs) at which the animal reacts and reports the nociception threshold.
Individual pain threshold measurements (up to 100) are stored in the internal memory, and can be downloaded post experiment. Recently an embedded statistical computation has been included in the electronic device of the algometer. This is a very useful feature that as been very well received and used by users of large numbers of tests. The display shows in real time the mean, standard deviation and variation coefficient from groups of animals (rats or mice). This feature also allows the user to cancel any analgesia test incorrectly performed.
NEW: Wireless
A full range of devices, including the Rodent Pincher now feature our new Wireless technology: thanks to the wireless transmitter on the operator’s wrist, there is no more cable between the electronic unit with the display and the sensors.
This new, wireless technology offers numerous advantages:
• Improved User range of motion : free from annoying cables !
• Flexible setup within the lab : Design your behavior room with fewer limitations
• Get rid of the physical constraints: Focus on your experiment only !
Options
• Our optional BIO-CIS2 software for Windows sends directly the displayed values in an Excel (MS) sheet. This allows the user direct access to a ready report and options for further analysis, without any re-copy error. Supplied with an RS232 cable.
• External pod to display a led light or produce a sound when reaching a preset threshold of force.
• Analog output and cable
• TTL output
• Additional sensor tests : our Electronic Von Frey probe, Small Animal Algometer come with their own calibration modules that are recognized by the electronic unit.Supplied with
• Bench control unit (batteries and main power supply)
• One rat or mice pincher, capacity 2000 grs
• Carrying case
• Footswitch for zeroing the force and having the hands 'free'
• RS232 output
• User manualNew system! AlgoKit
AlgoKit
A COMPLETE SOLUTION FOR ALL SITUATIONS
INVOLVING PAIN MEASUREMENT ON RODENTS
MULTIPLE PROBES, ONE CONTROL UNIT AND SOFTWARE APPLICATION
INVOLVING PAIN MEASUREMENT ON RODENTS
MULTIPLE PROBES, ONE CONTROL UNIT AND SOFTWARE APPLICATION
You may consider our new ALGOKIT package to expand the scope of your possibilities. In order to offer an answer to all your requests regarding different situations of pain measurement, Bioseb is proud to present an innovative, complete solution combining our Static Weight Bearing, including its state-of-the art touchscreen, color console, with up to 3 sensors to be chosen among our Electronic Von Frey, Rodent Pincher and Small animal Algometer, all connected to one unique Control Unit.
Features:
• Flexible instrument when a quantitative sensory testing (QST) is needed
• Compatible with our BIO-CIS2 software to improve repeatability in nociceptive testing
BIO-RP-WRS
Data sheet
- Data output
- RS232 for PC
- Number of animals
- Individual rat or mouse (2 different pinchers)
- Power supply
- Battery powered, this instrument is autonomous. Possibility of using a 220V/110V 50hz/60hz adapter
- Range
- 0 to 2000 grams
- Resolution
- 0.1 gram or 0.001 N
- Applications
- Arthritis & Osteoarthritis
Central Nervous System (CNS)
Cross-disciplinary subjects
Mood Disorders
Pain
Sensory system
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[title] => Bioscreening of the spacerized complex BIS -2-Pyridyl--3--1- 2- 4-Triazolyl- propane and 11-Hydroxy-1- 1-Ethylidenediphosphonic acid
[paragraph_crop] => Bioscreening of the spacerized complex BIS (2-Pyridyl)-3-(1, 2, 4-Triazolyl) propane and [...]
[image_presente] =>
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[title] => EFFECT OF 1-HYDROXY-1-1-ETHYLIDENDIPHOSPHONE ACID- BIS-2-PYRIDYL-1-2-4-TRIAZOLYL-3-PROPANE AND THEIR ADDUCT ON THE PAIN SENSITIVITY OF RATS PYRIDYL-1-2-4-TRIAZOLYL-3-PROPANE AND THEIR ADDUCT ON THE PAIN SENSITIVITY OF RATS
[paragraph_crop] => EFFECT OF 1-HYDROXY-1,1-ETHYLIDENDIPHOSPHONE ACID, BIS(2-PYRIDYL-1,2,4-TRIAZOLYL-3)PROPANE AND [...]
[image_presente] =>
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[title] => Mechanical allodynia & Hyperlagesia
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[title] => INFLUENCE OF 1-HYDROXY-1-1-ETHYLIDENDIPHOSPHONE ACID AND BIS -2-PYRIDYL-1-2-4-TRIAZOLYL-3- PROPANE ON PAIN SENSITIVITY OF RAT FEMALES
[paragraph_crop] => INFLUENCE OF 1-HYDROXY-1,1-ETHYLIDENDIPHOSPHONE ACID AND BIS (2-PYRIDYL-1,2,4-TRIAZOLYL-3) [...]
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[url] => https://bioseb.com/en/news/effect-of-1-hydroxy-1-1-thylidendiphosphone-acid--bis-2-pyridyl-1-2-4-triazolyl-3-propane-and-their-adduct-on-the-pain-sensitivty-of-rats-n1156
[title] => Effect of 1-Hydroxy-1-1-thylidendiphosphone Acid- Bis-2-Pyridyl-1-2-4-Triazolyl-3-Propane and their adduct on the pain sensitivty of Rats
[paragraph_crop] => Effect of 1-Hydroxy-1,1-thylidendiphosphone Acid, Bis(2-Pyridyl-1,2,4-Triazolyl-3)Propane and [...]
[image_presente] =>
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[url] => https://bioseb.com/en/news/cholecalciferol--vitamin-d-3--reduces-rat-neuropathic-pain-by-modulating-opioid-signaling-n1123
[title] => Cholecalciferol -Vitamin D 3- Reduces Rat Neuropathic Pain by Modulating Opioid Signaling
[paragraph_crop] => Cholecalciferol (Vitamin D 3) Reduces Rat Neuropathic Pain by Modulating Opioid Signaling
[image_presente] =>
[date] => 2019-04-18 00:00:00
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[id] => 1101
[url] => https://bioseb.com/en/news/analgesic-and-anti-edemic-properties-of-etifoxine-in-models-of-inflammatory-sensitization-n1101
[title] => Analgesic and anti-edemic properties of etifoxine in models of inflammatory sensitization
[paragraph_crop] => Analgesic and anti-edemic properties of etifoxine in models of inflammatory sensitization
[image_presente] =>
[date] => 2019-02-15 00:00:00
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[title] => Inflammatory pain
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[976] => Array
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[id] => 976
[url] => https://bioseb.com/en/news/sphingosine-1-phosphate-and-the-s1p3-receptor-initiate-neuronal-retraction-via-rhoa-and-rock-associated-with-crmp2-phosphorylation-n976
[title] => Sphingosine-1-Phosphate and the S1P3 Receptor Initiate Neuronal Retraction via RhoA and ROCK Associated with CRMP2 Phosphorylation
[paragraph_crop] => Sphingosine-1-Phosphate and the S1P3 Receptor Initiate Neuronal Retraction via RhoA/ROCK [...]
[image_presente] =>
[date] => 2017-10-10 00:00:00
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[title] => Central Nervous System (CNS)
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[title] => Nerve regeneration
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[title] => Publications
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[url] => https://bioseb.com/en/news/application-of-calibrated-forceps-for-assessing-mechanical-nociception-with-high-time-resolution-in-mice-n1102
[title] => Application of calibrated forceps for assessing mechanical nociception with high time resolution in mice
[paragraph_crop] => Application of calibrated forceps for assessing mechanical nociception with high time [...]
[image_presente] =>
[date] => 2017-02-17 00:00:00
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[title] => Mechanical allodynia & Hyperlagesia
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[title] => Pain
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[842] => Array
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[id] => 842
[url] => https://bioseb.com/en/news/anti-nociceptive-properties-of-shikonin--in-vitro-and-in-vivo-studies-n842
[title] => Anti-nociceptive properties of shikonin- In vitro and In vivo studies
[paragraph_crop] => Anti-nociceptive properties of shikonin: In vitro and In vivo studies
[image_presente] =>
[date] => 2016-07-01 00:00:00
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[title] => Miscellaneous research domains
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[title] => Publications
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[id] => 839
[url] => https://bioseb.com/en/news/a-new-population-of-parvocellular-oxytocin-neurons-controlling-magnocellular-neuron-activity-and-inflammatory-pain-processing-n839
[title] => A New Population of Parvocellular Oxytocin Neurons Controlling Magnocellular Neuron Activity and Inflammatory Pain Processing
[paragraph_crop] => A New Population of Parvocellular Oxytocin Neurons Controlling Magnocellular Neuron Activity [...]
[image_presente] =>
[date] => 2016-03-16 00:00:00
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[title] => Publications
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[id] => 748
[url] => https://bioseb.com/en/news/pharmacodynamic-evaluation-of-sustained-release-of-peg-and-pla-formulation-including-bupivacane-or-ropivacane-versus-0-25-bupivacane-after-sciatic-nerve-block-in-rat-n748
[title] => Pharmacodynamic Evaluation of Sustained Release of PEG and PLA Formulation Including Bupivacaïne or Ropivacaïne versus 0-25% Bupivacaïne After Sciatic Nerve Block in Rat
[paragraph_crop] => Pharmacodynamic Evaluation of Sustained Release of PEG/PLA Formulation Including Bupivacaïne [...]
[image_presente] =>
[date] => 2015-10-27 00:00:00
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[title] => Cross-disciplinary subjects
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[title] => Pharmacology
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[id] => 753
[url] => https://bioseb.com/en/news/long-term-behavioral-effects-in-a-rat-model-of-prolonged-postnatal-morphine-exposure--n753
[title] => Long-Term Behavioral Effects in a Rat Model of Prolonged Postnatal Morphine Exposure-
[paragraph_crop] => Long-Term Behavioral Effects in a Rat Model of Prolonged Postnatal Morphine Exposure.
[image_presente] =>
[date] => 2015-10-01 00:00:00
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[805] => Array
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[id] => 805
[url] => https://bioseb.com/en/news/en3427--a-novel-cationic-aminoindane-with-long-acting-local-anesthetic-properties-n805
[title] => EN3427- A Novel Cationic Aminoindane with Long-Acting Local Anesthetic Properties
[paragraph_crop] => EN3427: A Novel Cationic Aminoindane with Long-Acting Local Anesthetic Properties
[image_presente] =>
[date] => 2015-04-01 00:00:00
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[title] => Central Nervous System (CNS)
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[38] => Array
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[title] => Nerve regeneration
[link_rewrite] => Nerve-regeneration
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[2] => Array
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[title] => Publications
[link_rewrite] => publications
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[678] => Array
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[id] => 678
[url] => https://bioseb.com/en/news/corticosterone-analgesia-is-mediated-by-the-spinal-production-of-neuroactive-metabolites-that-enhance-gabaergic-inhibitory-transmission-on-dorsal-horn-rat-neurons-n678
[title] => Corticosterone analgesia is mediated by the spinal production of neuroactive metabolites that enhance GABAergic inhibitory transmission on dorsal horn rat neurons
[paragraph_crop] => Corticosterone analgesia is mediated by the spinal production of neuroactive metabolites that [...]
[image_presente] =>
[date] => 2015-02-01 00:00:00
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[id_prestablog_categorie] => 27
[title] => General pain
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[title] => Pain
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[title] => Publications
[link_rewrite] => publications
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[664] => Array
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[id] => 664
[url] => https://bioseb.com/en/news/characterization-of-the-fast-gabaergic-inhibitory-action-of-etifoxine-during-spinal-nociceptive-processing-in-male-rats-n664
[title] => Characterization of the fast GABAergic inhibitory action of etifoxine during spinal nociceptive processing in male rats
[paragraph_crop] => Characterization of the fast GABAergic inhibitory action of etifoxine during spinal [...]
[image_presente] =>
[date] => 2014-12-26 00:00:00
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[id_prestablog_categorie] => 27
[title] => General pain
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[title] => Publications
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[706] => Array
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[id] => 706
[url] => https://bioseb.com/en/news/peripheral-nerve-regeneration-and-ngf-dependent-neurite-outgrowth-of-adult-sensory-neurons-converge-on-stat3-phosphorylation-downstream-of-neuropoietic-cytokine-receptor-gp130--n706
[title] => Peripheral nerve regeneration and NGF-dependent neurite outgrowth of adult sensory neurons converge on STAT3 phosphorylation downstream of neuropoietic cytokine receptor gp130-
[paragraph_crop] => Peripheral nerve regeneration and NGF-dependent neurite outgrowth of adult sensory neurons [...]
[image_presente] =>
[date] => 2014-09-24 00:00:00
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[title] => Central Nervous System (CNS)
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[title] => Nerve regeneration
[link_rewrite] => Nerve-regeneration
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[title] => Publications
[link_rewrite] => publications
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[568] => Array
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[id] => 568
[url] => https://bioseb.com/en/news/plasma-glucocorticoids-differentially-modulate-phasic-and-tonic-gaba-inhibition-during-early-postnatal-development-in-rat-spinal-lamina-ii-n568
[title] => Plasma glucocorticoids differentially modulate phasic and tonic GABA inhibition during early postnatal development in rat spinal lamina II
[paragraph_crop] => Plasma glucocorticoids differentially modulate phasic and tonic GABA inhibition during early [...]
[image_presente] =>
[date] => 2014-06-23 00:00:00
[categories] => Array
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(
[id_prestablog_categorie] => 27
[title] => General pain
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[title] => Pain
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[title] => Publications
[link_rewrite] => publications
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[502] => Array
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[id] => 502
[url] => https://bioseb.com/en/news/feasibility-and-repeatability-of-cold-and-mechanical-quantitative-sensory-testing-in-normal-dogs-n502
[title] => Feasibility and repeatability of cold and mechanical quantitative sensory testing in normal dogs
[paragraph_crop] => Feasibility and repeatability of cold and mechanical quantitative sensory testing in normal dogs
[image_presente] =>
[date] => 2013-10-28 00:00:00
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[title] => Publications
[link_rewrite] => publications
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[506] => Array
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[id] => 506
[url] => https://bioseb.com/en/news/long-lasting-spinal-oxytocin-analgesia-is-ensured-by-the-stimulation-of-allopregnanolone-synthesis-which-potentiates-gabaa-receptor-mediated-synaptic-inhibition--n506
[title] => Long-Lasting Spinal Oxytocin Analgesia Is Ensured by the Stimulation of Allopregnanolone Synthesis Which Potentiates GABAA Receptor-Mediated Synaptic Inhibition
[paragraph_crop] => Long-Lasting Spinal Oxytocin Analgesia Is Ensured by the Stimulation of Allopregnanolone [...]
[image_presente] =>
[date] => 2013-10-16 00:00:00
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[title] => Hot & Cold Perception
[link_rewrite] => Hot-Cold-Perception
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[title] => Mechanical allodynia & Hyperlagesia
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[title] => Pain
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[title] => Publications
[link_rewrite] => publications
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[title] => Sensory system
[link_rewrite] => Sensory-system
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[545] => Array
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[id] => 545
[url] => https://bioseb.com/en/news/etifoxine-stimulates-allopregnanolone-synthesis-in-the-spinal-cord-to-produce-analgesia-in-experimental-mononeuropathy-n545
[title] => Etifoxine stimulates allopregnanolone synthesis in the spinal cord to produce analgesia in experimental mononeuropathy
[paragraph_crop] => Etifoxine stimulates allopregnanolone synthesis in the spinal cord to produce analgesia in [...]
[image_presente] =>
[date] => 2013-07-24 00:00:00
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[title] => General pain
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[title] => Mechanical allodynia & Hyperlagesia
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[title] => Neuropathic pain
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[title] => Pain
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[title] => Publications
[link_rewrite] => publications
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[473] => Array
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[id] => 473
[url] => https://bioseb.com/en/news/phenotyping-the-function-of-trpv1-expressing-sensory-neurons-by-targeted-axonal-silencing--n473
[title] => Phenotyping the function of TRPV1-expressing sensory neurons by targeted axonal silencing-
[paragraph_crop] => Phenotyping the function of TRPV1-expressing sensory neurons by targeted axonal silencing.
[image_presente] =>
[date] => 2013-01-02 00:00:00
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[title] => General pain
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[title] => Mechanical allodynia & Hyperlagesia
[link_rewrite] => Mechanical-allodynia-hyperlagesia
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[10] => Array
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[title] => Pain
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[title] => Publications
[link_rewrite] => publications
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[447] => Array
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[id] => 447
[url] => https://bioseb.com/en/news/long-term-changes-in-trigeminal-ganglionic-and-thalamic-neuronal-activities-following-inferior-alveolar-nerve-transection-in-behaving-rats--n447
[title] => Long-Term Changes in Trigeminal Ganglionic and Thalamic Neuronal Activities following Inferior Alveolar Nerve Transection in Behaving Rats
[paragraph_crop] => Long-Term Changes in Trigeminal Ganglionic and Thalamic Neuronal Activities following Inferior [...]
[image_presente] =>
[date] => 2012-11-30 00:00:00
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[title] => General pain
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[31] => Array
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[title] => Orofacial pain
[link_rewrite] => Orofacial-pain
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[title] => Pain
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[2] => Array
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[title] => Publications
[link_rewrite] => publications
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[481] => Array
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[id] => 481
[url] => https://bioseb.com/en/news/effects-of-peripheral-inflammation-on-the-blood-spinal-cord-barrier-n481
[title] => Effects of peripheral inflammation on the blood spinal cord barrier
[paragraph_crop] => Effects of peripheral inflammation on the blood spinal cord barrier
[image_presente] =>
[date] => 2012-06-18 00:00:00
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[title] => General pain
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[title] => Inflammatory pain
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[10] => Array
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[title] => Pain
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[2] => Array
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[title] => Publications
[link_rewrite] => publications
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[354] => Array
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[id] => 354
[url] => https://bioseb.com/en/news/erythropoietin-restores-c-fiber-function-and-prevents-pressure-ulcer-formation-in-diabetic-mice---n354
[title] => Erythropoietin Restores C-Fiber Function and Prevents Pressure Ulcer Formation in Diabetic Mice-
[paragraph_crop] => Erythropoietin Restores C-Fiber Function and Prevents Pressure Ulcer Formation in Diabetic Mice.
[image_presente] =>
[date] => 2011-11-30 00:00:00
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[title] => Miscellaneous research domains
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[title] => Publications
[link_rewrite] => publications
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[350] => Array
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[id] => 350
[url] => https://bioseb.com/en/news/endogenous-opioids-released-during-non-nociceptive-environmental-stress-induce-latent-pain-sensitization-via-a-nmda-dependent-process---n350
[title] => Endogenous Opioids Released During Non-Nociceptive Environmental Stress Induce Latent Pain Sensitization Via a NMDA-Dependent Process-
[paragraph_crop] => Endogenous Opioids Released During Non-Nociceptive Environmental Stress Induce Latent Pain [...]
[image_presente] =>
[date] => 2011-10-01 00:00:00
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[title] => Publications
[link_rewrite] => publications
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[328] => Array
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[id] => 328
[url] => https://bioseb.com/en/news/evidence-for-a-differential-opioidergic-involvement-in-the-analgesic-effect-of-antidepressants--prediction-for-efficacy-in-animal-models-of-neuropathic-pain--n328
[title] => Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants- prediction for efficacy in animal models of neuropathic pain?
[paragraph_crop] => Evidence for a differential opioidergic involvement in the analgesic effect of [...]
[image_presente] =>
[date] => 2011-06-30 00:00:00
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[title] => Miscellaneous research domains
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[title] => Publications
[link_rewrite] => publications
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[293] => Array
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[id] => 293
[url] => https://bioseb.com/en/news/the-rat-intervertebral-disk-degeneration-pain-model--relationships-between-biological-and-structural-alterations-and-pain---n293
[title] => The rat intervertebral disk degeneration pain model- relationships between biological and structural alterations and pain-
[paragraph_crop] => The rat intervertebral disk degeneration pain model: relationships between biological and [...]
[image_presente] =>
[date] => 2011-05-30 00:00:00
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[title] => Chronic pain
[link_rewrite] => Chronic-pain
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[21] => Array
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[title] => Joints
[link_rewrite] => Joints
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[72] => Array
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[id_prestablog_categorie] => 72
[title] => Lower back & discs
[link_rewrite] => Lower-back-discs
)
[29] => Array
(
[id_prestablog_categorie] => 29
[title] => Neuropathic pain
[link_rewrite] => Neuropathic-pain
)
[10] => Array
(
[id_prestablog_categorie] => 10
[title] => Pain
[link_rewrite] => Pain
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[301] => Array
(
[id] => 301
[url] => https://bioseb.com/en/news/phosphorylation-of-spinal-n-methyl-d-aspartate-receptor-nr1-subunits-by-extracellular-signal-regulated-kinase-in-dorsal-horn-neurons-and-microglia-contributes-to-diabetes-induced-painful-neuropathy---n301
[title] => Phosphorylation of spinal N-methyl-d-aspartate receptor NR1 subunits by extracellular signal-regulated kinase in dorsal horn neurons and microglia contributes to diabetes-induced painful neuropathy-
[paragraph_crop] => Phosphorylation of spinal N-methyl-d-aspartate receptor NR1 subunits by extracellular [...]
[image_presente] =>
[date] => 2011-02-01 00:00:00
[categories] => Array
(
[26] => Array
(
[id_prestablog_categorie] => 26
[title] => Miscellaneous research domains
[link_rewrite] => Miscellaneous-research-domains
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[285] => Array
(
[id] => 285
[url] => https://bioseb.com/en/news/magnesium-attenuates-chronic-hypersensitivity-and-spinal-cord-nmda-receptor-phosphorylation-in-a-rat-model-of-diabetic-neuropathic-pain---n285
[title] => Magnesium attenuates chronic hypersensitivity and spinal cord NMDA receptor phosphorylation in a rat model of diabetic neuropathic pain-
[paragraph_crop] => Magnesium attenuates chronic hypersensitivity and spinal cord NMDA receptor phosphorylation in [...]
[image_presente] =>
[date] => 2010-11-01 00:00:00
[categories] => Array
(
[26] => Array
(
[id_prestablog_categorie] => 26
[title] => Miscellaneous research domains
[link_rewrite] => Miscellaneous-research-domains
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[250] => Array
(
[id] => 250
[url] => https://bioseb.com/en/news/differential-anti-neuropathic-pain-effects-of-tetrodotoxin-in-sciatic-nerve--versus-infraorbital-nerve-ligated-rats--behavioral--pharmacological-and-immunohistochemical-investigations---n250
[title] => Differential anti-neuropathic pain effects of tetrodotoxin in sciatic nerve- versus infraorbital nerve-ligated rats – Behavioral- pharmacological and immunohistochemical investigations-
[paragraph_crop] => Differential anti-neuropathic pain effects of tetrodotoxin in sciatic nerve- versus [...]
[image_presente] =>
[date] => 2010-02-28 00:00:00
[categories] => Array
(
[26] => Array
(
[id_prestablog_categorie] => 26
[title] => Miscellaneous research domains
[link_rewrite] => Miscellaneous-research-domains
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[244] => Array
(
[id] => 244
[url] => https://bioseb.com/en/news/reduction-and-prevention-of-vincristine-induced-neuropathic-pain-symptoms-by-the-non-benzodiazepine-anxiolytic-etifoxine-are-mediated-by-3-reduced-neurosteroids--n244
[title] => Reduction and prevention of vincristine-induced neuropathic pain symptoms by the non-benzodiazepine anxiolytic etifoxine are mediated by 3_-reduced neurosteroids-
[paragraph_crop] => Reduction and prevention of vincristine-induced neuropathic pain symptoms by the [...]
[image_presente] =>
[date] => 2009-12-15 00:00:00
[categories] => Array
(
[28] => Array
(
[id_prestablog_categorie] => 28
[title] => Inflammatory pain
[link_rewrite] => Inflammatory-pain
)
[10] => Array
(
[id_prestablog_categorie] => 10
[title] => Pain
[link_rewrite] => Pain
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[241] => Array
(
[id] => 241
[url] => https://bioseb.com/en/news/increase-in-morphine-antinociceptive-activity-by-a-p-glycoprotein-inhibitor-in-cisplatin-induced-neuropathy--n241
[title] => Increase in morphine antinociceptive activity by a P-glycoprotein inhibitor in cisplatin-induced neuropathy-
[paragraph_crop] => Increase in morphine antinociceptive activity by a P-glycoprotein inhibitor in [...]
[image_presente] =>
[date] => 2009-11-06 00:00:00
[categories] => Array
(
[26] => Array
(
[id_prestablog_categorie] => 26
[title] => Miscellaneous research domains
[link_rewrite] => Miscellaneous-research-domains
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[199] => Array
(
[id] => 199
[url] => https://bioseb.com/en/news/combination-of-microsurgery-and-gene-therapy-for-spinal-dorsal-root-injury-repair--n199
[title] => Combination of Microsurgery and Gene Therapy for Spinal Dorsal Root Injury Repair-
[paragraph_crop] => Combination of Microsurgery and Gene Therapy for Spinal Dorsal Root Injury Repair.
[image_presente] =>
[date] => 2009-06-30 00:00:00
[categories] => Array
(
[11] => Array
(
[id_prestablog_categorie] => 11
[title] => Central Nervous System (CNS)
[link_rewrite] => Central-Nervous-System-(CNS)
)
[10] => Array
(
[id_prestablog_categorie] => 10
[title] => Pain
[link_rewrite] => Pain
)
[33] => Array
(
[id_prestablog_categorie] => 33
[title] => Postoperative pain
[link_rewrite] => Postoperative-pain
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
[39] => Array
(
[id_prestablog_categorie] => 39
[title] => Spinal Cord
[link_rewrite] => Spinal-Cord
)
)
)
[179] => Array
(
[id] => 179
[url] => https://bioseb.com/en/news/fast-non-genomic-effects-of-progesterone-derived-neurosteroids-on-nociceptive-thresholds-and-pain-symptoms--n179
[title] => Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms-
[paragraph_crop] => Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and [...]
[image_presente] =>
[date] => 2008-10-31 00:00:00
[categories] => Array
(
[27] => Array
(
[id_prestablog_categorie] => 27
[title] => General pain
[link_rewrite] => General-pain
)
[36] => Array
(
[id_prestablog_categorie] => 36
[title] => Mechanical allodynia & Hyperlagesia
[link_rewrite] => Mechanical-allodynia-hyperlagesia
)
[10] => Array
(
[id_prestablog_categorie] => 10
[title] => Pain
[link_rewrite] => Pain
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[170] => Array
(
[id] => 170
[url] => https://bioseb.com/en/news/specific-antinociceptive-activity-of-cholest-4-en-3-one--oxime--tro19622--in-experimental-models-of-painful-diabetic-and-chemotherapy-induced-neuropathy--n170
[title] => Specific Antinociceptive Activity of Cholest-4-en-3-one- Oxime -TRO19622- in Experimental Models of Painful Diabetic and Chemotherapy-Induced Neuropathy-
[paragraph_crop] => Specific Antinociceptive Activity of Cholest-4-en-3-one, Oxime (TRO19622) in Experimental [...]
[image_presente] =>
[date] => 2008-08-30 00:00:00
[categories] => Array
(
[26] => Array
(
[id_prestablog_categorie] => 26
[title] => Miscellaneous research domains
[link_rewrite] => Miscellaneous-research-domains
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[120] => Array
(
[id] => 120
[url] => https://bioseb.com/en/news/mechanical--thermal-and-formalin-induced-nociception-is-differentially-altered-in-5-ht1a-and---5-ht1b-and---5-ht2a-and---5-ht3a-and--and-5-htt-and--knock-out-male-mice--n120
[title] => Mechanical- thermal and formalin-induced nociception is differentially altered in 5-HT1A_ and _- 5-HT1B_ and _- 5-HT2A_ and _- 5-HT3A_ and _ and 5-HTT_ and _ knock-out male mice-
[paragraph_crop] => Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A_/_, [...]
[image_presente] =>
[date] => 2007-08-30 00:00:00
[categories] => Array
(
[26] => Array
(
[id_prestablog_categorie] => 26
[title] => Miscellaneous research domains
[link_rewrite] => Miscellaneous-research-domains
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[117] => Array
(
[id] => 117
[url] => https://bioseb.com/en/news/antinociceptive-efficacy-of-lacosamide-in-rat-models-for-tumor--and-chemotherapy-induced-cancer-pain--n117
[title] => Antinociceptive efficacy of lacosamide in rat models for tumor- and chemotherapy-induced cancer pain-
[paragraph_crop] => Antinociceptive efficacy of lacosamide in rat models for tumor- and chemotherapy-induced [...]
[image_presente] =>
[date] => 2007-06-22 00:00:00
[categories] => Array
(
[26] => Array
(
[id_prestablog_categorie] => 26
[title] => Miscellaneous research domains
[link_rewrite] => Miscellaneous-research-domains
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[116] => Array
(
[id] => 116
[url] => https://bioseb.com/en/news/agmatine-induces-antihyperalgesic-effects-in-diabetic-rats-and-a-superadditive-interaction-with-r---3--2-carboxypiperazine-4-yl--propyl-1-phosphonic-acid--a-n-methyl-d-aspartate-receptor-antagonist--n116
[title] => Agmatine Induces Antihyperalgesic Effects in Diabetic Rats and a Superadditive Interaction with R-–--3--2-Carboxypiperazine-4-yl--propyl-1-phosphonic Acid- a N-Methyl-d-aspartate-Receptor Antagonist-
[paragraph_crop] => Agmatine Induces Antihyperalgesic Effects in Diabetic Rats and a Superadditive Interaction [...]
[image_presente] =>
[date] => 2007-06-05 00:00:00
[categories] => Array
(
[26] => Array
(
[id_prestablog_categorie] => 26
[title] => Miscellaneous research domains
[link_rewrite] => Miscellaneous-research-domains
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[106] => Array
(
[id] => 106
[url] => https://bioseb.com/en/news/lacosamide--a-review-of-preclinical-properties--n106
[title] => Lacosamide- A Review of Preclinical Properties-
[paragraph_crop] => Lacosamide: A Review of Preclinical Properties.
[image_presente] =>
[date] => 2007-03-30 00:00:00
[categories] => Array
(
[26] => Array
(
[id_prestablog_categorie] => 26
[title] => Miscellaneous research domains
[link_rewrite] => Miscellaneous-research-domains
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[83] => Array
(
[id] => 83
[url] => https://bioseb.com/en/news/the-transcription-factor-fosb-is-recruited-by-inflammatory-pain--n83
[title] => The transcription factor _FosB is recruited by inflammatory pain-
[paragraph_crop] => The transcription factor _FosB is recruited by inflammatory pain.
[image_presente] =>
[date] => 2006-09-30 00:00:00
[categories] => Array
(
[28] => Array
(
[id_prestablog_categorie] => 28
[title] => Inflammatory pain
[link_rewrite] => Inflammatory-pain
)
[10] => Array
(
[id_prestablog_categorie] => 10
[title] => Pain
[link_rewrite] => Pain
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[79] => Array
(
[id] => 79
[url] => https://bioseb.com/en/news/antinociceptive-efficacy-of-lacosamide-in-a-rat-model-for-painful-diabetic-neuropathy--n79
[title] => Antinociceptive efficacy of lacosamide in a rat model for painful diabetic neuropathy-
[paragraph_crop] => Antinociceptive efficacy of lacosamide in a rat model for painful diabetic neuropathy.
[image_presente] =>
[date] => 2006-06-06 00:00:00
[categories] => Array
(
[26] => Array
(
[id_prestablog_categorie] => 26
[title] => Miscellaneous research domains
[link_rewrite] => Miscellaneous-research-domains
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[70] => Array
(
[id] => 70
[url] => https://bioseb.com/en/news/calibrated-forceps--a-sensitive-and-reliable-tool-for-pain-and-analgesia-studies--n70
[title] => Calibrated Forceps- A Sensitive and Reliable Tool for Pain and Analgesia Studies-
[paragraph_crop] => Calibrated Forceps: A Sensitive and Reliable Tool for Pain and Analgesia Studies.
[image_presente] =>
[date] => 2006-01-30 00:00:00
[categories] => Array
(
[26] => Array
(
[id_prestablog_categorie] => 26
[title] => Miscellaneous research domains
[link_rewrite] => Miscellaneous-research-domains
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
)
)
[62] => Array
(
[id] => 62
[url] => https://bioseb.com/en/news/inflammatory-pain-upregulates-spinal-inhibition-via-endogenous-neurosteroid-production--n62
[title] => Inflammatory Pain Upregulates Spinal Inhibition via Endogenous Neurosteroid Production-
[paragraph_crop] => Inflammatory Pain Upregulates Spinal Inhibition via Endogenous Neurosteroid Production.
[image_presente] =>
[date] => 2005-12-14 00:00:00
[categories] => Array
(
[48] => Array
(
[id_prestablog_categorie] => 48
[title] => Hot & Cold Perception
[link_rewrite] => Hot-Cold-Perception
)
[28] => Array
(
[id_prestablog_categorie] => 28
[title] => Inflammatory pain
[link_rewrite] => Inflammatory-pain
)
[36] => Array
(
[id_prestablog_categorie] => 36
[title] => Mechanical allodynia & Hyperlagesia
[link_rewrite] => Mechanical-allodynia-hyperlagesia
)
[10] => Array
(
[id_prestablog_categorie] => 10
[title] => Pain
[link_rewrite] => Pain
)
[2] => Array
(
[id_prestablog_categorie] => 2
[title] => Publications
[link_rewrite] => publications
)
[13] => Array
(
[id_prestablog_categorie] => 13
[title] => Sensory system
[link_rewrite] => Sensory-system
)
)
)
)
1Number of publications:
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