Publications

Dernière publication 19/06/2017

Transcranial direct current stimulation enhances recovery from motor deficits fo

Prenatal cerebrovascular stroke can cause permanent damage to the brain followed by deficits in neuro-muscular functioning. We hypothesize that...

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    [title] => Transcranial direct current stimulation enhances recovery from motor deficits fo
    [paragraph] => Transcranial direct current stimulation enhances recovery from motor deficits following hypoxia-ischemia in neonatal rats
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Authors
C. L. Anderson, B. J. Tessler , T. B. DeMarse, M. Douglas-Escobar, C. Rossignol, R. Nelson, A. K. Kasinadhuni, M. King, P. Bose, M. D. Weiss, P. R. Carney  

 Lab
University of Florida, Crayton Pruitt Family Department of Biomedical Engineering, , Gainesville, Florida
Journal
Opne Access Text
Abstract
Prenatal cerebrovascular stroke can cause permanent damage to the brain followed by deficits in neuro-muscular functioning. We hypothesize that recovery can be enhanced by transcranial direct current stimulation (tDCS) through changes in cortical plasticity. Unilateral hypoxia-ischemia (HI) was produced in rats on postnatal day 7 (P7). At P21, anodal tDCS was given to HI pups for 7 days. tDCS treated HI pups showed improved weight, grip strength, gait, motor function, and concentrations of brain-derived neurotropic factor cortex ratios compared to non-treated HI animal controls. These findings support tDCS following HI as an effective therapeutic for neonatal stroke.
BIOSEB Instruments Used
Grip strength test (BIO-GS3)
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Une méthode simple pour quantifier objectivement la force musculaire des rats et souris et l'effet de drogues, toxines, maladies musculaires (ex: myopathie) et neurodégénératives. Cette mesure de force est souvent employée en association avec le test de coordination motrice ROTAROD: un sujet présentant une coordination normale montrera des résultats médiocres en cas de faible force musculaire. Un must pour vos recherches sur l'activité, la coordination et le contrôle musculaire: particulièrement utile pour vos études sur les maladies de Parkinson et Huntington.
Nouveautés GS4 - 2023: Écran couleur rétroéclairé (meilleure lisibilité), pédale de remise à zéro, durée de batterie optimisée, taille de mémoire augmentée à 500 valeurs, compteur d'animaux, port USB (transfert de données/charge)

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