Publications

Dernière publication 19/08/2015

Assessment of muscle mass and strength in mice

Muscle weakness is an important phenotype of many diseases that is linked to impaired locomotion and increased mortality. The force that a muscle...

Array
(
    [id_prestablog_news] => 744
    [id_shop] => 1
    [date] => 2015-08-19 00:00:00
    [date_modification] => 2024-02-09 14:15:12
    [langues] => ["1","2"]
    [actif] => 1
    [slide] => 0
    [url_redirect] => 
    [average_rating] => 
    [number_rating] => 
    [author_id] => 1
    [featured] => 0
    [prim_key] => 1454
    [id_lang] => 2
    [title] => Assessment of muscle mass and strength in mice
    [paragraph] => Assessment of muscle mass and strength in mice
    [content] => 
Authors
Andrea Bonetto,	Daniel C Andersson	& David L Waning

 Lab
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA
Journal
BoneKEy Reports
Abstract
Muscle weakness is an important phenotype of many diseases that is linked to impaired locomotion and increased mortality. The force that a muscle can generate is determined predominantly by muscle size, fiber type and the excitation–contraction coupling process. Here we describe methods for the histological assessment of whole muscle to determine fiber cross-sectional area and fiber type, determination of changes in myocyte size using C2C12 cells, in vivo functional tests and measurement of contractility in dissected whole muscles. The extensor digitorum longus and soleus muscles are ideally suited for whole-muscle contractility, and dissection of these muscles is described.
BIOSEB Instruments Used
Grip strength test (BIO-GS3)
    [meta_description] => 
    [meta_keywords] => http://www.nature.com/bonekeyreports/2015/150819/bonekey2015101/full/bonekey2015101.html
    [meta_title] => 
    [link_rewrite] => assessment-of-muscle-mass-and-strength-in-mice
    [actif_langue] => 1
    [read] => 1008
    [count_comments] => 0
    [id] => 744
    [categories] => Array
        (
            [2] => Array
                (
                    [id_prestablog_categorie] => 2
                    [title] => Publications
                    [link_rewrite] => publications
                )

            [20] => Array
                (
                    [id_prestablog_categorie] => 20
                    [title] => Système musculaire
                    [link_rewrite] => Systeme-musculaire
                )

            [63] => Array
                (
                    [id_prestablog_categorie] => 63
                    [title] => Système musculaire général
                    [link_rewrite] => Systeme-musculaire-general
                )

        )

    [authors] => 
    [paragraph_crop] => Assessment of muscle mass and strength in mice
    [link_for_unique] => 1
    [products_liaison] => Array
        (
            [48] => Array
                (
                    [name] => Test d'agrippement
                    [description_short] => 
Une méthode simple pour quantifier objectivement la force musculaire des rats et souris et l'effet de drogues, toxines, maladies musculaires (ex: myopathie) et neurodégénératives. Cette mesure de force est souvent employée en association avec le test de coordination motrice ROTAROD: un sujet présentant une coordination normale montrera des résultats médiocres en cas de faible force musculaire. Un must pour vos recherches sur l'activité, la coordination et le contrôle musculaire: particulièrement utile pour vos études sur les maladies de Parkinson et Huntington.
Nouveautés GS4 - 2023: Écran couleur rétroéclairé (meilleure lisibilité), pédale de remise à zéro, durée de batterie optimisée, taille de mémoire augmentée à 500 valeurs, compteur d'animaux, port USB (transfert de données/charge)

                    [thumb] => 
                    [img_empty] => /var/www/vhosts/de3310.ispfr.net/bioseb2024/modules/prestablog/views/img/product_link_white.jpg
                    [image_presente] => 1
                    [link] => https://bioseb.com/fr/activite-systeme-moteur-coordination/48-grip-strength-test.html
                )

        )

)
1