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Dernière publication 28/09/2017

The different baseline characteristics of cognitive behavior test between Mongol

The Mongolian gerbil is a popular laboratory animal useful across many research fields. In the area of cognitive behavioral research the gerbil...

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    [title] => The different baseline characteristics of cognitive behavior test between Mongol
    [paragraph] => The different baseline characteristics of cognitive behavior test between Mongolian gerbils and rats
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Authors
S.Wand, D. Feng, Y. Li, Y. Wang, X. Sun, X. Li, C. Li, Z. Chen, X.Du

 Lab
S.Wand, D. Feng, Y. Li, Y. Wang, X. Sun, X. Li, C. Li, Z. Chen, X.Du
Journal
Behavioural Brain Research
Abstract
The Mongolian gerbil is a popular laboratory animal useful across many research fields. In the area of cognitive behavioral research the gerbil have been shown exhibit an anxiety-like profile on the elevated plus-maze, and they could be useful as an animal model for testing anxiolytics and antidepressants. However, there are few reports that thoroughly describe the behavioral characteristics of the gerbils in common cognitive behavior tests. In the present study, we used 7 behavior tests to detect the baseline characteristics of the gerbils and compare them to the Sprague Dawley rats. Collectively, the gerbils showed significantly different behavior characteristics in the open field test, elevated plus maze, grip strength, social interaction and fear conditioning compared to the rats. However, no difference was found between gerbils and rats in sucrose preference or Barnes maze test. The data showed that the Mongolian gerbil exhibited higher social interaction and exploratory activity, but lower conditioning fear and grip strength compared with the rats. These results indicate that the gerbil may be a sensitive animal model in behavioral brain research particularly in the areas of anxiety and fear.
BIOSEB Instruments Used
Grip strength test (BIO-GS3)
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                    [description_short] => 
Une méthode simple pour quantifier objectivement la force musculaire des rats et souris et l'effet de drogues, toxines, maladies musculaires (ex: myopathie) et neurodégénératives. Cette mesure de force est souvent employée en association avec le test de coordination motrice ROTAROD: un sujet présentant une coordination normale montrera des résultats médiocres en cas de faible force musculaire. Un must pour vos recherches sur l'activité, la coordination et le contrôle musculaire: particulièrement utile pour vos études sur les maladies de Parkinson et Huntington.
Nouveautés GS4 - 2023: Écran couleur rétroéclairé (meilleure lisibilité), pédale de remise à zéro, durée de batterie optimisée, taille de mémoire augmentée à 500 valeurs, compteur d'animaux, port USB (transfert de données/charge)

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