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Dernière publication 01/09/2017

Impact of SEL1L deletion in central nervous system on the behavior of mice

The Objective was to investigate the role of endoplasmic reticulum protein SEL1L in the maintenance of physiological activities of the central...

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    [title] => Impact of SEL1L deletion in central nervous system on the behavior of mice
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Authors
J Wang, Q Liu, Z Pan, Z Zhou, Q Long

 Lab
Research Center of Laboratory Animals and the Genome Rseearch center of Cambridge-Soochow University, Suzhou, China
Journal
Chinese Journal of Comparative Medicine
Abstract
The Objective was to investigate the role of endoplasmic reticulum protein SEL1L in the maintenance of physiological activities of the central nervous system in mammals. The data of the postnatal survival time, the body weight and the behavioral indicators such as balance coordination, locomotion and anxiety of the mice show that the condition of the NKO mice is significantly worse than that of the WT mice, indicating an important role of SEL1L in the maintenance of physiological functions of the nervous system.
BIOSEB Instruments Used
Grip strength test (BIO-GS3)
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Une méthode simple pour quantifier objectivement la force musculaire des rats et souris et l'effet de drogues, toxines, maladies musculaires (ex: myopathie) et neurodégénératives. Cette mesure de force est souvent employée en association avec le test de coordination motrice ROTAROD: un sujet présentant une coordination normale montrera des résultats médiocres en cas de faible force musculaire. Un must pour vos recherches sur l'activité, la coordination et le contrôle musculaire: particulièrement utile pour vos études sur les maladies de Parkinson et Huntington.
Nouveautés GS4 - 2023: Écran couleur rétroéclairé (meilleure lisibilité), pédale de remise à zéro, durée de batterie optimisée, taille de mémoire augmentée à 500 valeurs, compteur d'animaux, port USB (transfert de données/charge)

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