Publications

Dernière publication 01/01/2022

Garlic exosome-like nanoparticles reverse high-fat diet induced obesity via the

Obesity is becoming a global epidemic and reversing the pathological processes underlying obesity and metabolic co-morbidities is challenging....

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    [title] => Garlic exosome-like nanoparticles reverse high-fat diet induced obesity via the 
    [paragraph] => Garlic exosome-like nanoparticles reverse high-fat diet induced obesity via the gut/brain axis
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Authors
K Sundaram, J Mu, A Kumar et al

 Lab
James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA
Journal
Theranostics
Abstract
Obesity is becoming a global epidemic and reversing the pathological processes underlying obesity and metabolic co-morbidities is challenging. Obesity induced chronic inflammation including brain inflammation is a hallmark of obesity via the gut-brain axis. The objective of this study was to develop garlic exosome-like nanoparticles (GaELNs) that inhibit systemic as well as brain inflammatory activity and reverse a HFD induced obesity in mice.
BIOSEB Instruments Used
Grip strength test (BIO-GS3)

Keywords/Topics
Obésité & Surpoids
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Une méthode simple pour quantifier objectivement la force musculaire des rats et souris et l'effet de drogues, toxines, maladies musculaires (ex: myopathie) et neurodégénératives. Cette mesure de force est souvent employée en association avec le test de coordination motrice ROTAROD: un sujet présentant une coordination normale montrera des résultats médiocres en cas de faible force musculaire. Un must pour vos recherches sur l'activité, la coordination et le contrôle musculaire: particulièrement utile pour vos études sur les maladies de Parkinson et Huntington.
Nouveautés GS4 - 2023: Écran couleur rétroéclairé (meilleure lisibilité), pédale de remise à zéro, durée de batterie optimisée, taille de mémoire augmentée à 500 valeurs, compteur d'animaux, port USB (transfert de données/charge)

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