Publications

Dernière publication 01/11/2026

Interactions between SSR504734, a selective glycine transporter type 1 inhibitor

Studies suggest the potential involvement of glycine in seizures and epilepsy; however, no currently available antiseizure medications directly target

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    [title] => Interactions between SSR504734, a selective glycine transporter type 1 inhibitor
    [paragraph] => Interactions between SSR504734, a selective glycine transporter type 1 inhibitor, and antiseizure drugs: pharmacodynamic and pharmacokinetic studies in mice
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Authors
Nikola Gapińska, Piotr Wlaź, Elżbieta Wyska, Artur Świerczek, Krzysztof Kamiński, Marcin Jakubiec, Katarzyna Ciepiela, Michał Abram, Gniewomir Latacz, Ewa Poleszak, Katarzyna Socała

Lab
Journal
Neuropharmacology
Abstract
Studies suggest the potential involvement of glycine in seizures and epilepsy; however, no currently available antiseizure medications directly target
Keywords/Topics
mice studies; interactions; ssr504734; antiseizure drugs; pharmacodynamic and pharmacokinetic studies; glycine; seizures; epilepsy; studies; glycine transporter
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Une méthode simple pour quantifier objectivement la force musculaire des rats et souris et l'effet de drogues, toxines, maladies musculaires (ex: myopathie) et neurodégénératives. Cette mesure de force est souvent employée en association avec le test de coordination motrice ROTAROD: un sujet présentant une coordination normale montrera des résultats médiocres en cas de faible force musculaire. Un must pour vos recherches sur l'activité, la coordination et le contrôle musculaire: particulièrement utile pour vos études sur les maladies de Parkinson et Huntington.
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