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Dernière publication 01/08/2024

Developmental activity-based anorexia alters hippocampal non-genomic stress resp

Anorexia nervosa (AN) is characterized by hyperactivation of the hypothalamic-pituitary-adrenal axis and cognitive deficits. However, little is known

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    [title] => Developmental activity-based anorexia alters hippocampal non-genomic stress resp
    [paragraph] => Developmental activity-based anorexia alters hippocampal non-genomic stress response and induces structural instability and spatial memory impairment in female rats
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Authors
Francesca Mottarlini, Giorgia Targa, Beatrice Rizzi, Fabio Fumagalli, Lucia Caffino



 Lab


Journal
Progress in Neuro-Psychopharmacology and Biological Psychiatry


Abstract
Anorexia nervosa (AN) is characterized by hyperactivation of the hypothalamic-pituitary-adrenal axis and cognitive deficits. However, little is known 


Keywords/Topics
Anorexia nervosa;Adolescence;Corticosterone;Glutamatergic synapse;Dendritic spine;Cognition;Hippocampus
BIOSEB Instruments Used:
Basic spontaneous activity wheels (BIO-ACTIVW-M)

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La Roue Instrumentée pour Exercice Spontané est une méthode simple pour mesurer l'activité spontanée de rongeurs dans leur cage de vie - particulièrement adapté à la souris, ces roues se déclinent aussi chez le rat. L'électronique associée à un logiciel mesure la distance parcourue, la vitesse (Moy, min, max), l'accélération, le temps et le nombre d'accès à la roue. Un outil idéal pour les criblages de drogues, ainsi que les études sur le phénotypage et les maladies neuromusculaires. Chaque roue intègre un totalisateur embarqué (distances) consultable sans logiciel. Un nouveau logiciel est disponible pour contrôler jusqu'à 64 roues.


Instrument for ratsInstrument for mice

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