Activity, Motor Control & Coordination
Pain - Thermal Allodynia / Hyperalgesia
Pain - Spontaneous Pain - Postural Deficit
Pain - Mechanical Allodynia / Hyperalgesia
Anxiety & Depression Disorder
Learning/Memory - Attention - Addiction
Physiology & Respiratory Research
Metabolism - Food & Drink Intake
Pain
Central Nervous System (CNS)
Neurodegeneration
Sensory system
Motor control
Mood Disorders
Other disorders
Muscular system
Joints
Metabolism
Cross-disciplinary subjects
Preclinical studies and opioids: role in crisis management in the United States Authors
Lab
Dalhousie University, Halifax, NS, Canada
Journal
Osteoarthritis and Cartilage
Abstract
Post-traumatic osteoarthritis (PTOA) accounts for 12% of all osteoarthritis cases. Lesions of the medial meniscus are a risk factor for the development of PTOA and also increase the susceptibility to neuropathic pain. While PTOA pain can stem from instability-induced joint degeneration, we hypothesise that a proportion of the pain is due to nerve damage. This study aimed to characterise PTOA pain from multiple angles in the medial meniscus transection (MMT) model of joint instability.