General muscular system Scientific Publications

Latest publication 07/16/2026

GBT1118 voxelotor analog improves skeletal muscle function, phenotype and signif

We examined the effect of GBT1118, a sickle hemoglobin polymerization inhibitor on skeletal muscle grip strength and phenotype in Townes sickle cell d

Array
(
    [id_prestablog_news] => 2480
    [id_shop] => 1
    [date] => 2026-07-16 00:00:00
    [date_modification] => 2026-07-16 00:00:00
    [langues] => ["1","2"]
    [actif] => 1
    [slide] => 0
    [url_redirect] => 
    [average_rating] => 
    [number_rating] => 
    [author_id] => 1
    [featured] => 0
    [ishero] => 0
    [prim_key] => 4827
    [id_lang] => 1
    [title] => GBT1118 voxelotor analog improves skeletal muscle function, phenotype and signif
    [paragraph] => GBT1118 voxelotor analog improves skeletal muscle function, phenotype and significantly reduced serum myopathy biomarker GDF15 in sickle cell disease mice
    [content] => 
Authors
Marja M. Hurley, Wei He, Liping Xiao

Lab
Journal
Biochemical and Biophysical Research Communications
Abstract
We examined the effect of GBT1118, a sickle hemoglobin polymerization inhibitor on skeletal muscle grip strength and phenotype in Townes sickle cell d
Keywords/Topics
sickle cell disease mice; skeletal muscle grip strength; forelimb grip strength; mice; gbt1118 voxelotor analog; skeletal muscle function; phenotype; gbt1118; d muscle strength; bioseb
    [meta_description] => 
    [meta_keywords] => https://www.sciencedirect.com/science/article/pii/S0006291X26007011
    [meta_title] => 
    [link_rewrite] => GBT1118-voxelotor-analog-improves-skeletal-muscle-function-phenotype-and-significantly-reduced-serum-myopathy-biomarker-GDF15-in-sickle-cell-disease-mice
    [actif_langue] => 1
    [read] => 42
    [count_comments] => 0
    [id] => 2480
    [categories] => Array
        (
            [63] => Array
                (
                    [id_prestablog_categorie] => 63
                    [title] => General muscular system
                    [link_rewrite] => General-muscular-system
                )

            [2] => Array
                (
                    [id_prestablog_categorie] => 2
                    [title] => Publications
                    [link_rewrite] => publications
                )

        )

    [authors] => 
    [paragraph_crop] => GBT1118 voxelotor analog improves skeletal muscle function, phenotype and significantly [...]
    [link_for_unique] => 1
    [products_liaison] => Array
        (
            [48] => Array
                (
                    [name] => Grip strength test
                    [description_short] => 
An easy way to objectively quantify the muscular strength of mice and rats, and to assess the effect of drugs, toxins, muscular (i.e. myopathy) and neurodegenerative diseases on muscular degeneration. It is widely used in conjunction with the ROTAROD motor coordination test: a normally coordinated rodent will show a decreased latency to fall off the rotating rod if its muscular strength is low. The Grip Strength Test is a must for your research on activity, motor control & coordination, and is particularly well suited for studies on Parkinson's & Huntington's disease.
New features GS4 - 2023: Color display with permanent backlight screen for easier reading, reset by footswitch, Improved battery time, Larger data memory of 500 values, Animal counter, USB port (charging/data transfer)

                    [thumb] => 
                    [img_empty] => /var/www/vhosts/de3310.ispfr.net/bioseb2024/modules/prestablog/views/img/product_link_white.jpg
                    [image_presente] => 1
                    [link] => https://bioseb.com/en/activity-motor-control-coordination/48-grip-strength-test.html
                )

        )

)
1