Cancer Scientific Publications

Latest publication 09/01/2026

Pre-clinical cancer cachexia causes glucose hypermetabolism prior to overt weigh

Cancer cachexia is a life-threatening complication of advanced malignancies, driven by profound systemic metabolic reprogramming and anorexia. Insulin

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    [title] => Pre-clinical cancer cachexia causes glucose hypermetabolism prior to overt weigh
    [paragraph] => Pre-clinical cancer cachexia causes glucose hypermetabolism prior to overt weight loss
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Authors
Emma Frank, Kaspar W. Persson, Pauline Morigny, Zakarias Kefil Jensen Ogueboule, Tang Cam Phung Pham, Jonas R. Knudsen, Maria Rohm, Lykke Sylow, Steffen H. Raun

Lab
Journal
Molecular Metabolism
Abstract
Cancer cachexia is a life-threatening complication of advanced malignancies, driven by profound systemic metabolic reprogramming and anorexia. Insulin
Keywords/Topics
insulin grip strength assessment; pre-clinical cancer cachexia; glucose hypermetabolism; overt weight loss; advanced malignancies; profound systemic metabolic reprogramming; anorexia; bioseb

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An easy way to objectively quantify the muscular strength of mice and rats, and to assess the effect of drugs, toxins, muscular (i.e. myopathy) and neurodegenerative diseases on muscular degeneration. It is widely used in conjunction with the ROTAROD motor coordination test: a normally coordinated rodent will show a decreased latency to fall off the rotating rod if its muscular strength is low. The Grip Strength Test is a must for your research on activity, motor control & coordination, and is particularly well suited for studies on Parkinson's & Huntington's disease.


New features GS4 - 2023: Color display with permanent backlight screen for easier reading, reset by footswitch, Improved battery time, Larger data memory of 500 values, Animal counter, USB port (charging/data transfer)


forrats.pngformice.png

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