Myostatin (MSTN) negatively regulates skeletal muscle (SM) growth, and its over activity suppresses myogenic differentiation, promoting muscle atrophy
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[title] => Therapeutic potential of Amentoflavone against myostatin for skeletal muscle atr
[paragraph] => Therapeutic potential of Amentoflavone against myostatin for skeletal muscle atrophy treatment: An in silico, in vitro, and in vivo study
[content] => Authors
Jeong Ho Lim, Syed Sayeed Ahmad, Eun Ju Lee, Jae-Moon Choi, Inho Choi
Lab
Journal
Phytomedicine
Abstract
Myostatin (MSTN) negatively regulates skeletal muscle (SM) growth, and its over activity suppresses myogenic differentiation, promoting muscle atrophy
Keywords/Topics
activity; therapeutic potential; amentoflavone; myostatin; skeletal muscle atrophy treatment; silico; vitro; vivo study myostatin; mstn; skeletal muscle
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[title] => Muscular atrophy
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[description_short] => An easy way to objectively quantify the muscular strength of mice and rats, and to assess the effect of drugs, toxins, muscular (i.e. myopathy) and neurodegenerative diseases on muscular degeneration. It is widely used in conjunction with the ROTAROD motor coordination test: a normally coordinated rodent will show a decreased latency to fall off the rotating rod if its muscular strength is low. The Grip Strength Test is a must for your research on activity, motor control & coordination, and is particularly well suited for studies on Parkinson's & Huntington's disease.
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