Using Microfluidics for Fast- Accurate Measurement of Lysozyme Nucleation Kinetics-

Authors
M. Ildefonso, N. Candoni, S. Veesler.


Lab
Centre Interdisciplinaire de Nanoscience de Marseille CINAM—CNRS, Marseille, France.

Journal
Crystal Growth and Design

Abstract
Here we measure lysozyme nucleation kinetics using an easy-to-use and simply constructed microfluidics setup previously described. We confirm that microfluidics is a direct, accurate, and fast method to measure nucleation frequency using only a few milligrams of molecules. Moreover, our microfluidics setup, by diminishing crystallizer volumes, increases the experimental supersaturation range accessible and can be applied to all water-soluble molecules.

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