Publications

Dernière publication 26/03/2022

Codonopsis lanceolata and Its Active Component Tangshenoside I Ameliorate Skelet

Skeletal muscle atrophy is caused by aging, disuse, malnutrition, and several diseases. However, there are still no effective drugs or treatments...

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    [title] => Codonopsis lanceolata and Its Active Component Tangshenoside I Ameliorate Skelet
    [paragraph] => Codonopsis lanceolata and Its Active Component Tangshenoside I Ameliorate Skeletal Muscle Atrophy via Regulating the PI3K and Akt and SIRT1 and PGC-1alpha Pathways
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Authors
TY Kim, KT Park, SY Choung 

 Lab
Kyung Hee University, Seoul, Republic of Korea.
Journal
Phytomedicine
Abstract
Skeletal muscle atrophy is caused by aging, disuse, malnutrition, and several diseases. However, there are still no effective drugs or treatments for muscle atrophy. Codonopsis lanceolata (CL), a traditional medicinal plant and food, has been reported to have anti-oxidative, anti-inflammatory, anti-tumor, and anti-obesity effects. This study aimed to investigate the efficacy and active component of CL on muscle atrophy in vitro and to confirm the effect of CL and its active component on muscle atrophy and the underlying molecular mechanisms in vivo.
BIOSEB Instruments Used
Grip strength test (BIO-GS3)

Keywords/Topics
Atrophie musculaire
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Une méthode simple pour quantifier objectivement la force musculaire des rats et souris et l'effet de drogues, toxines, maladies musculaires (ex: myopathie) et neurodégénératives. Cette mesure de force est souvent employée en association avec le test de coordination motrice ROTAROD: un sujet présentant une coordination normale montrera des résultats médiocres en cas de faible force musculaire. Un must pour vos recherches sur l'activité, la coordination et le contrôle musculaire: particulièrement utile pour vos études sur les maladies de Parkinson et Huntington.
Nouveautés GS4 - 2023: Écran couleur rétroéclairé (meilleure lisibilité), pédale de remise à zéro, durée de batterie optimisée, taille de mémoire augmentée à 500 valeurs, compteur d'animaux, port USB (transfert de données/charge)

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