Activity, Motor Control & Coordination
Pain - Thermal Allodynia / Hyperalgesia
Pain - Spontaneous Pain - Postural Deficit
Pain - Mechanical Allodynia / Hyperalgesia
Anxiety & Depression Disorder
Learning/Memory - Attention - Addiction
Physiology & Respiratory Research
Metabolism - Food & Drink Intake
Pain
Central Nervous System (CNS)
Neurodegeneration
Sensory system
Motor control
Mood Disorders
Other disorders
Muscular system
Joints
Metabolism
Cross-disciplinary subjects
Preclinical studies and opioids: role in crisis management in the United States Authors
R Gao, T Ye, Z Zhu et al
Lab
Shanghai Jiao Tong University Affiliated Sixth People' Hospitaliated to Shanghai Jiaotong University
Journal
ResearchSquare
Abstract
Acute pain is the primary symptom of tendinopathy, and mast cells activation is a nonnegligible cause. Currently, safe and effective treatment for acute pain in tendinopathy is still lacking. This study was aimed to explore the analgesic effect of iPSC-derived mesenchymal stem cell-derived small extracellular vesicles (iMSC-sEVs) on acute pain and further investigate the underlying mechanisms in tendinopathy.
BIOSEB Instruments Used:
Electronic Von Frey 5 with embedded camera (BIO-EVF5),Static Weight Bearing Touch: Incapacitance Test (BIO-SWB-TOUCH-M),Electronic Von Frey 4 (BIO-EVF4)
