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Dernière publication 18/05/2024

DJ-1 protects cell death from a mitochondrial oxidative stress due to GBA1 defic

GBA1 mutations are the most common genetic risk factor for development of Parkinson's disease (PD). The loss of catalytic activity in GBA1, as well a

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    [title] => DJ-1 protects cell death from a mitochondrial oxidative stress due to GBA1 defic
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Authors
Nam, Younwoo, Na, Jiyeon, Ma, Shi-Xun, Park, Haeun, Park, Hyeonwoo, Lee, Eunmin, Kim, Hyerynn, Jang, Sang-Min, Ko, Han Seok, Kim, Sangjune



 Lab


Journal
Genes & Genomics


Abstract
GBA1 mutations are the most common genetic risk factor for development of Parkinson's disease (PD). The loss of catalytic activity in GBA1, as well a


Keywords/Topics
GBA1 deficiency ;Parkinson's disease; DJ - 1 Oxidative stress
BIOSEB Instruments Used:
Grip strength test (BIO-GS4)

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                    [description_short] => 
Une méthode simple pour quantifier objectivement la force musculaire des rats et souris et l'effet de drogues, toxines, maladies musculaires (ex: myopathie) et neurodégénératives. Cette mesure de force est souvent employée en association avec le test de coordination motrice ROTAROD: un sujet présentant une coordination normale montrera des résultats médiocres en cas de faible force musculaire. Un must pour vos recherches sur l'activité, la coordination et le contrôle musculaire: particulièrement utile pour vos études sur les maladies de Parkinson et Huntington.


Nouveautés GS4 - 2023: Écran couleur rétroéclairé (meilleure lisibilité), pédale de remise à zéro, durée de batterie optimisée, taille de mémoire augmentée à 500 valeurs, compteur d'animaux, port USB (transfert de données/charge)


Instrument for ratsInstrument for mice

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