Publications

Dernière publication 04/12/2019

Arthritis sensory and motor scale- predicting functional deficits from the clini

In the collagen-induced arthritis (CIA) mouse model, inflammation readouts are usually quantified using operator-dependent clinical scoring...

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    [title] => Arthritis sensory and motor scale- predicting functional deficits from the clini
    [paragraph] => Arthritis sensory and motor scale: predicting functional deficits from the clinical score in collagen-induced arthritis
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Authors
AL Mausset-Bonnefont, M Cren, R Vicente, J Quentin

 Lab
IRMB, University of Montpellier, INSERM, Montpellier, France
Journal
Arthritis Research & Therapy
Abstract
In the collagen-induced arthritis (CIA) mouse model, inflammation readouts are usually quantified using operator-dependent clinical scoring systems, and no systematic relationship with functional deficits has been detected. In this study, we extensively quantified sensory and motor deficits in CIA mice during natural disease progression and therapeutic treatment. Then, we used these data to build a scale to predict functional deficits on the basis of the classical clinical score.
BIOSEB Instruments Used
Static Weight Bearing Touch: Incapacitance Test (BIO-SWB-TOUCH-M),Infrared Actimeter (LE8815)

Keywords/Topics
Arthrite & Arthrose; Articulations
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