Douleurs neuropathiques - page 6 - Publications Scientifiques

Dernière publication 01/01/2026

GPRASP1 deletion suppresses antinociceptive tolerance during chronic activation

Delta-opioid receptor (DOR) agonists display antinociceptive properties with less adverse effects than morphine derivatives and other opioids targetin

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    [title] => GPRASP1 deletion suppresses antinociceptive tolerance during chronic activation 
    [paragraph] => GPRASP1 deletion suppresses antinociceptive tolerance during chronic activation of delta opioid receptor in persistent pain
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Authors
Juliette Kaeffer, Marie-Laure Straub, Glenn-Marie Le Coz, Raphaëlle Quillet, Valérie Kugler, Nathalie Petit-Demoulière, Manon Gerum, Gabrielle Zeder-Lutz, Stéphane Doridot, Michael Dumas, Johana Chicher, Philippe Hammann, Philippe Marin, Franck Vandermoere, Dominique Massotte, Frédéric Simonin, Sandra Lecat

Lab
Journal
Biomedicine & Pharmacotherapy
Abstract
Delta-opioid receptor (DOR) agonists display antinociceptive properties with less adverse effects than morphine derivatives and other opioids targetin
Keywords/Topics
persistent pain delta-opioid receptor; gprasp1 deletion; antinociceptive tolerance; chronic activation; delta; opioid receptor; agonists; antinociceptive properties; less adverse effects; morphine derivatives
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Un algomètre rapide et précis, basé sur une pince instrumentée: une alternative au test de Randall-Selitto. Ce nouvel algésimètre développé par Bioseb selon Luis-Delgado et al. (2005) permet des tests nociceptifs précis et la mesure du seuil de douleur mécanique sur pattes de rats ou de souris, avec une contrainte minimale. Maintenant en version sans-fil, pour être libéré des câbles!

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