
A unique setup for the automation of the Open Field test for rats and mice : 3D-camera based...
A unique setup for the automation of the Open Field test for rats and mice : 3D-camera based...
Discover our productsAn easy way to objectively quantify the muscular strength of mice and rats, and to assess the...
Discover our productsThe BIOSEB Spontaneous Activity Wheel offers an effective solution for quantifying rodent...
Discover our productsThe uncomplicated way to monitor rodent activity over several days from their home cage...
Discover our productsThese small animal treadmills are used for forced exercise training and accurate testing of...
Discover our productsRotarod provides an easy way to test the motor activity in rodents (mouse or rat) - an ideal...
Discover our productsFor testing animal's thermal sensitivity to pain resulting from exposure to heat or cold: the...
Discover our productsAn operator independent test to study pain thresholds in rodents (mouse and rat) by assessing...
Discover our productsNew and improved! The operator-independent Thermal Gradient Test used to show favorite...
Discover our productsParticularly sensitive for studying the analgesic properties of pharmacological substances
Discover our productsThe advanced version of our Dynamic Weight Bearing Test for rodents (rats and mice) allows for...
Discover our productsA unique device that provides automated measurement of weight bearing and force distribution...
Discover our productsA NEW software for increasing the repeatability of nociceptive tests: by recording the reflex...
Discover our productsA quick solution to determine the mechanical sensitivity threshold in rodents (mice and rats)....
Discover our productsThe latest evolution of Bioseb's Electronic Von Frey instrument for determining the mechanical...
Discover our productsNew ROBUST and modular cages to gently hold rodents (rats or mice) during nociceptive and...
Discover our productsAn economical and versatile solution for when flexible quantitative sensory testing (QST) is...
Discover our productsDedicated to small animals, like mice and rats, Smalgo is a pressure-based analgesimeter...
Discover our productsBioseb's version 5 of the Tail Suspension Test system, based on both strain sensors and video...
Discover our productsNEW ! A complete (hardware + software), dedicated and automated solution for the Elevated Plus...
Discover our productsA unique setup for the automation of the Open Field test for rats and mice : 3D-camera based...
Discover our productsOpen-field test - ARENA ONLY - used to evaluate of animal's basal activity and its evolution for...
Discover our productsThe new Forced Swimming Test system from Bioseb uses a dual approach: Combining a double input...
Discover our productsA brand new innovative setup for the automation of the Novel Object Recognition Test : 3D-camera...
Discover our productsOpen-field test - ARENA ONLY - used to evaluate of animal's basal activity and its evolution for...
Discover our productsAn entirely modular experimental enclosure designed to conduct operant conditioning procedures...
Discover our productsA standard experimental chamber for automated or manual assessment of conditioned place...
Discover our productsThe ETH-401 is a bridge amplifier for various transducers that provides four channels of...
Discover our productsThe IX-118 is a fast 100 Khz, high-resolution data acquisition system suitable for most data...
Discover our productsThe ETH-256 is a 2 channels high performance, general-purpose life science research amplifier,...
Discover our productsFull-featured multi-channel stimulator for neuromuscular stimulation
Discover our productsThe From now On POPULAR IX-214 Unit is the perfect rugged, reliable, four-channel data...
Discover our productsThe OXYLET system - Physiocage is a modular system allowing the integration of respiratory...
Discover our productsInnovative and appropriate equipment for measuring food/liquid consumption and correlated motor...
Discover our productsAn economical, high performance Oxygen and Carbon Dioxide Analyzer with sampling rates fast...
Discover our productsNEW ! A complete (hardware + software), dedicated and automated solution for the Elevated Plus Maze test, featuring unprecedented simplicity to run these very popular protocols. A user-friendly and innovative solution for your research on anxiety, depression and the screening of anxiolytic drugs.
Presentation
The Elevated Plus-Maze is a commonly used test to assess anxiety-like behavior in laboratory animals (rats/mice). Based on the natural fear that rodents have for height and open spaces, the Elevated Plus Maze is a general research tool in neurobiological anxiety field and usually uses to screen the efficacy of drugs.
The Elevated-Plus-Maze (EPM) is one of the very first tests used by neuroscientists to evaluate anxiety-like behavior in rodents and the most widely used test after the Open Field to evaluate anxiolitic or anxiogenic effects. The EPM could also be considered among other various other tests for the screening of mice strains. The EPM can also be used to assess side effects of psychiatric disorders treatments.
Bioseb proposes an all-inclusive solution for the Elevated-Plus-Maze (EPM) test with hardware and software components.
Video tracking is a very good way to automate the Elevated-Plus-Maze (EPM) test for rats and mice, which is the the reason why we have designed a dedicated software application, the EPM-3C, to run any EPM protocols (compatible with hardware from Bioseb or other brands), based on a powerful video tracking system. The zone transition is matched perfectly with the manual scoring by using specific morphologic detection. The tracking zones (open/closed arms, center) are really easy to define and once they are, the software is optimized to be setup easily and starts with just three clicks, in order to assist, speed up and simplify your experiments.
The Bioseb EPM Software gives all the information you need from your EPM experiment and most of the parameters are computed in real-time.
Regarding the hardware, Bioseb has designed its EPM test for mice and rats according to the standard dimensions widely used in the field. The corridors of the Bioseb Elevated-Plus-Maze are made in high quality perpex, so that the material will not retain odors. Their light grey, non-reflective color makes them ideal to combine with video-tracking. Finally, the assembly of the equipment has been made really easy.
Tripod and industrial quality camera are also provided so you can start your experiments rapidly. Operating principle
The new EPM-3C solution from BIOSEB features unprecedented simplicity to run ELEVATED + MAZE protocols.
The test setting consists of a plus-shaped apparatus with two open and two enclosed arms, each with an open roof and elevated from the floor. The aversion of the rodents to open spaces leads into a restriction of movement to the enclosed arms.
Anxiety of rodents is directly linked to the proportion of time spent in closed arms versus the time spent in open arms. The more anxious the animals, the more time they spend in the closed arms.
To start the test, the animal is usually placed in the center zone of the maze and the duration of the experiment is generally about 5 minutes. The time spent in the various arms is the main data recorded during this test. The Bioseb software also gives the total number of entries in the various arms (open, closed and center), the global activity of the animal (calculated with the total distance of the animal during the test) and the latency of the first entrance to the open arm.
Your results can then be exported into Excel tables for further analysis.Supplied with :
The instrument comes with a maze, a camera, a USB cable, a boom stand and a software license.
Data sheet
Number of publications:
Bioseb's version 5 of the Tail Suspension Test system, based on both strain sensors and video acquisition, is the only fully...
A unique setup for the automation of the Open Field test for rats and mice : 3D-camera based technology is now capable of...
Open-field test - ARENA ONLY - used to evaluate of animal's basal activity and its evolution for rodents (rats and mice) in...
check_circle
check_circle