ALGOKIT Analgesimeter - Wireless

Presentation


In order to offer an answer to all your requests regarding different situations of pain measurement, Bioseb is proud to present an innovative, complete solution built around our state-of-the-art electronic console and combining up to 3 sensors amoung our Electronic Von Frey, Rodent Pincher and Small animal Algometer, all connected to one unique Control Unit.

Operating principles

Each of our pain threshold measurement instruments is based on a dedicated configuration which is originally stored in the associated console unit. We upgraded our system to save the configuration directly in the sensor devices, which now allows us to use several instruments with one single interface: our state-of-the-art touchscreen, color console. The 'Plug & Play' principle lets you simply switch off the console unit, change the sensor and resume your work.

This AlgoKit solution can be combined with our BIO-CIS2 software to improve the repeatability of reflex nociceptive tests. Stimulated pain resistance tests are well known to be highly operator-dependent. BIO-CIS2, by displaying in real time the force vs time, greatly helps the operator to improve their skills with the instrument and generate an impactful graphic representation of the data.

Features:

• Flexible instrument when a quantitative sensory testing (QST) is needed
• Compatible with our BIO-CIS2 software to improve repeatability in nociceptive testing
• Control unit features a large backlit display
• Statistical functions: mean and standard deviation values for each animal
• Internal memory with up to 100 values
• Runs on battery for more flexibility

Available sensors

Electronic Von Frey Presentation A quick solution to determine the mechanical sensitivity threshold in rodents (mice and rats). This precise and easy-to-use electronic instrument is a must-have reference for your research in analgesia, nociception, neuro-pathologies and post-operative pain. Stimulation Stimulation is usually applied on the rodent's hind paws. The paw's withdrawal following the mechanical stimulation is recorded as a response to the stimulus. Click here for more information

Pincher Presentation A fast and accurate algometer based on an instrumented pincher, allowing accurate nociceptive tests to measure mechanical pain threshold on rat or mouse limbs with minimal constraint. Stimulation The pressure is applied in the 'inter-digital' region, but can also be applied to the tail for rats. The instrument displays the force at which the animal reacts and reports the nociception threshold. Click here for more information

SMALGO Presentation Dedicated to small animals, like mice and rats, Smalgo is a pressure-based analgesimeter designed for easy assessment of sensitivity threshold. It is a must for osteo-arthritis and pain studies. Stimulation The operator adjusts the algometer to the thumb and applies a progressive pressure to the relevant location on the animal (usually joints or back), as if he was applying the pressure directly with his own finger. Click here for more information

 Dedicated BIO-CIS2 Software

Dedicated BIO-CIS2 Software

The multi-instrument BIO-CIS2 Software, by Bioseb, is compatible with all our mechanical allodynia / nociception measurement instruments and allows you to reduce inter-operator variability, which is an issue for these kinds of tests.

BIO-CIS2 can be used in two different ways with the Electronic Von Frey, Rodent Pincher and Smalgo:

• Direct measurement: When a sensor is connected to the BIO-CIS2 software during stimulation, the software displays the real-time graph of applied force vs time in real-time. Additional features allows the definition of a theoretical ramp (force/time) with upper-lower limits to be followed and displayed during the measurement and curves of a group of measures can be reloaded and displayed simultaneously for a graphical overview. These options greatly help the operator to improve their skills with the instrument and reduce operator-introduced variability and is useful for generating impactful figures.

• Indirect measurement: The control unit embeds an internal memory allowing you to store up to 100 values measured during your experiments. You will then be able to connect the instrument to the BIO-CIS2 software and transfer all your results to an Excel spreadsheet.

Domains of application

• Analgesia
• Nociception
• Inflammation
• Neuro-pathologies
• Post-operative pain
• Quantitative Sensory Testing (QST)