Pain - Thermal Allodynia / Hyperalgesia

These instruments are suitable for investigating a broad range of pain models involving thermal stimuli, including neuropathic pain, inflammatory pain, and pain induced by nerve injury or peripheral sensitization. They are also valuable for evaluating the analgesic effects of pharmacological treatments targeting thermal pain pathways.

Our systems use precision temperature control, stable heating/cooling elements, and automated monitoring to maintain consistent and uniform stimuli. This consistency ensures that any observed changes in animal responses are attributable to differences in pain sensitivity or analgesic interventions rather than variability in the test conditions.

Yes. The Cold Hot Plate Test is specifically designed to assess both heat and cold sensitivity in a single platform. Similarly, the Thermal Gradient Test 2.0 and Thermal Place Preference assay can be configured to explore various temperature ranges, allowing comprehensive analyses of thermal hypersensitivity.

Our thermal tests are designed with animal welfare and data integrity in mind. Many of the systems, such as the Thermal Place Preference and Thermal Gradient Test, allow the animal to move freely and choose its preferred temperature zone, reducing handling and stress. Automated data acquisition and operator-independent test designs further minimize observer bias.

Yes. Data can be easily exported in standard formats compatible with common statistical, imaging, or electrophysiological analysis software. By integrating thermal pain data with other endpoints, researchers can form a comprehensive picture of pain mechanisms and treatment effects.

On-demand technical support is available from Bioseb. Services can include help with installation, hardware and software training, or protocol optimization, depending on the complexity of your equipment. For more information or to arrange assistance, please reach out through our contact form.