-Homo--harringtonine prevents endothelial inflammation through IRF-1 dependent downregulation of VCAM1 mRNA expression and inhibition of cell adhesion molecule protein biosynthesis

Authors
Luisa D. Burgers, Sarah Ciurus, Patrick Engel, Silvia Kuntschar, Rebecca Raue, Anastasiia Kiprina, Tobias Primke, Tobias Schmid, Andreas Weigert, Achim Schmidtko, Robert Fürst


Lab

Journal
Biomedicine & Pharmacotherapy

Abstract
The plant alkaloid homoharringtonine (HHT) is a Food and Drug Administration (FDA)-approved drug for the treatment of hematologic malignancies. In add

Keywords/Topics
harringtonine;prevents;endothelial;inflammation;through;dependent;downregulation;expression;inhibition;adhesion

BIOSEB Instruments Used:
Dynamic Weight Bearing 2.0 (BIO-DWB-DUAL)

Source :

https://www.sciencedirect.com/science/article/pii/S0753332224007911

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