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The BIOSEB Spontaneous Activity Wheel is an easy way to quantify rodent voluntary activity in their home cage environment. The embedded electronics perform a wide range of measurements, including: wheel revolutions, average/min/max speed, acceleration, utilization time, number of access events among others . A useful tool for studies on Drug Screening, Phenotyping Circadian Rhythms, and Neuromuscular Diseases; now with a software-independent LCD display and redesigned software controlling up to 64 wheels!
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Presentation
Bioseb Spontaneous Activity Wheel is an easy and cost-efficient way to quantify rodents' voluntary activity in the supplied home cage environment (Type IIL and III cages), with models available for both mice and rat. Measurements include the distance run in both directions, the number of wheel revolutions, average/min/max speed, acceleration, total time in the wheel, number of access events, and can be displayed in statistical form or sorted by custom time periods.
The system allows you to longitudinally monitor and record the parameters pertaining to the voluntary exercise of an animal, that can freely decide upon its timing and intensity over extended periods of time (several days or weeks) in order to analyze the differences in behavior and exercising patterns induced by drugs or surgical manipulation. Bioseb Spontaneous Activity Wheels are an ideal tool for studies on Drug Screening, Phenotyping, Circadian Rhythms, and Neuromuscular Diseases.
Operating principle

Highly reliable sensors offer an excellent angular resolution (22°) and time resolution (0.1 seconds) to accurately record spontaneous exercising behavior, even allowing the study of subject acceleration and power pattern.
A complete digital solutionis provided by Bioseb’s ACTIVW-SOFT software allowing you to monitor up to 64 cages simultaneously via an external connection to the PC USB port (up to 5 m between cage and PC).
Data sheet
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[title] => TRPV1 Channel Activated by the PGE2/EP4 Pathway Mediates Spinal Hypersensitivity in a Mouse Model of Vertebral Endplate Degeneration
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[title] => PGE2 and EP4 skeleton interoception activity reduces vertebral endplate porosity and spinal pain with low-dose celecoxib
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[title] => Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice
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[url] => https://bioseb.com/en/news/evoked-and-ongoing-pain-like-behaviours-in-a-rat-model-of-paclitaxel-induced-peripheral-neuropathy-n1035
[title] => Evoked and Ongoing Pain-Like Behaviours in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy
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[title] => Peripherally Acting _-Opioid Receptor Agonists Attenuate Ongoing Pain-associated Behavior and Spontaneous Neuronal Activity after Nerve Injury in Rats
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[title] => The Ca2 influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance
[paragraph_crop] => The Ca2+ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant [...]
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[title] => Oral Supplementation of Melatonin Protects against Fibromyalgia-Related Skeletal Muscle Alterations in Reserpine-Induced Myalgia Rats-
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[title] => The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in the Coq9 gene
[paragraph_crop] => The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in [...]
[image_presente] =>
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[title] => Inflammation-induced decrease in voluntary wheel running in mice- a nonreflexive test for evaluating inflammatory pain and analgesia-
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1Number of publications:
An easy way to objectively quantify the muscular strength of mice and rats, and to assess the effect of drugs, toxins,...
The BIOSEB Spontaneous Activity Wheel offers an effective solution for...
The uncomplicated way to monitor rodent activity over several days from their home cage without manual...
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