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Berberine inhibits NLRP3 inflammasome activation and proinflammatory macrophage M1 polarization to accelerate peripheral nerve regeneration

07/01/2024 Inflammation , Publications

Authors
Jun Sun, Qiuhua Zeng, Zhimin Wu, Lixin Huang, Tao Sun, Cong Ling, Baoyu Zhang, Chuan Chen, Hui Wang

Lab

Journal
Neurotherapeutics

Abstract
Berberine (BBR) has demonstrated potent anti-inflammatory effects by modulating macrophage polarization. Nevertheless, the precise mechanisms through

Keywords/Topics
Berberine;Peripheral nerve injury;NLRP3 inflammasome;Macrophage polarization;Inflammation

BIOSEB Instruments Used:
Electronic Von Frey - Wireless (BIO-EVF-WRS)

Source :

https://www.sciencedirect.com/science/article/pii/S1878747924000333

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