Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy

Authors
Elena R. Rhymes, Rebecca L. Simkin, Ji Qu, David Villarroel-Campos, Sunaina Surana, Yao Tong, Ryan Shapiro, Robert W. Burgess, Xiang-Lei Yang, Giampietro Schiavo, James N. Sleigh


Lab

Journal
Neurobiology of Disease

Abstract
Charcot-Marie-Tooth disease (CMT) is a genetic peripheral neuropathy caused by mutations in many functionally diverse genes. The aminoacyl-tRNA synthe

Keywords/Topics
Aminoacyl - tRNA synthetase ( ARS ) ;Charcot - Marie - tooth disease ( CMT ) ;Intravital imaging;Motor neuron;Neuromuscular junction

BIOSEB Instruments Used:
Grip strength test (BIO-GS4)

Source :

https://www.sciencedirect.com/science/article/pii/S0969996124001001

Related products

Grip strength test

Publication request

Thank you for your interest in our product range and your request for this publication, which will be sent to you if the research team and the journal allow it. Our commercial team will contact you as soon as possible.