Botulinum toxin -A--induced bone loss is associated with increased blood velocity and reduced vascular bone porosity

Authors
Moussa, Mahmoud S, de Vet, Taylor, Lebcir, Nadine, Zaslansky, Paul, Chalifour, Lorraine E, Willie, Bettina M, Komarova, Svetlana V


Lab

Journal
Journal of Bone and Mineral Research

Abstract
Abstract. Disuse-induced bone loss is a common consequence of spaceflight and prolonged bed rest. Intraosseous blood vessel volume and number are decreased

Keywords/Topics
botulinum toxin A; blood flow; mechanical unloading; bone loss; synchrotron imaging; osteocyte network analysis; vascular porosity

BIOSEB Instruments Used:
Automated 3D Open Field for Rats and Mice (BIO-OF-3C)

Source :

https://academic.oup.com/jbmr/advance-article-abstract/doi/10.1093/jbmr/zjaf057/8119140

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