GBT1118 voxelotor analog improves skeletal muscle function, phenotype and significantly reduced serum myopathy biomarker GDF15 in sickle cell disease mice

Authors
Marja M. Hurley, Wei He, Liping Xiao


Lab

Journal
Biochemical and Biophysical Research Communications

Abstract
We examined the effect of GBT1118, a sickle hemoglobin polymerization inhibitor on skeletal muscle grip strength and phenotype in Townes sickle cell d

Keywords/Topics
sickle cell disease mice; skeletal muscle grip strength; forelimb grip strength; mice; gbt1118 voxelotor analog; skeletal muscle function; phenotype; gbt1118; d muscle strength; bioseb

Source :

https://www.sciencedirect.com/science/article/pii/S0006291X26007011

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