Interactions between SSR504734, a selective glycine transporter type 1 inhibitor, and antiseizure drugs: pharmacodynamic and pharmacokinetic studies in mice

Authors
Nikola Gapińska, Piotr Wlaź, Elżbieta Wyska, Artur Świerczek, Krzysztof Kamiński, Marcin Jakubiec, Katarzyna Ciepiela, Michał Abram, Gniewomir Latacz, Ewa Poleszak, Katarzyna Socała


Lab

Journal
Neuropharmacology

Abstract
Studies suggest the potential involvement of glycine in seizures and epilepsy; however, no currently available antiseizure medications directly target

Keywords/Topics
mice studies; interactions; ssr504734; antiseizure drugs; pharmacodynamic and pharmacokinetic studies; glycine; seizures; epilepsy; studies; glycine transporter

Source :

https://www.sciencedirect.com/science/article/pii/S0028390826002200

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