Pathogenic IgG from long COVID patients with neurological sequelae triggers sensitive but not cognitive impairments upon transfer into mice

Authors
Mignolet, Margaux, Deroux, Catherine, Florkin, Thomas, Bielarz, Valéry, De Swert, Kathleen, Halloin, Nicolas, Sprimont, Lindsay, Ladang, Aurélie, George, Fabienne, Gilloteaux, Jacques, Abeloos, Laurence, Garin, Pierre, Van Weyenbergh, Johan, Jamoulle, Marc, Diederich, Claire, Gillet, Nicolas Albert, Bulpa, Pierre, Nicaise, Charles


Lab
URPhyM; NARILIS; Namur; Belgium; CHU Liège; Liège; Belgium; Biobanque; CHU-UCL Namur; Site Godinne; Yvoir; Belgium; NARILIS; CHU-UCL Namur; Namur; Belgium; Laboratoire d’Anatomie; Namur; Belgium; Rega Institute; KULeuven; Leuven; Belgium; URVI; NARILIS; Namur; Belgium; Authors and Affiliations

Journal
Acta Neuropathologica

Abstract
Approximately 30% of long COVID patients still experience neurological symptoms (brain fog, pain, chronic fatigue) more than 4 months after the onset of CO

Keywords/Topics
Long COVID; SARS-CoV-2; PASC; Nervous system; IgG passive transfer; Behavioral tests

BIOSEB Instruments Used:
Von Frey Filaments (BIO-VF-M)

Source :

https://link.springer.com/article/10.1007/s00401-026-03019-0

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