Puerarin promotes nerve regeneration and functional recovery after peripheral nerve injury by inhibiting ACSL4-dependent ferroptosis

Authors
Tao Sun, Lixin Huang, Yibo Zhao, Qin Sun, Xi Luo, Zhimin Wu, Jun Sun, Mingyang Li, Qingyi Huo, Hui Wang


Lab

Journal
International Journal of Biological Macromolecules

Abstract
Peripheral nerve injury (PNI) is a intractable disease with poor treatment efficacy, it's suggested that ferroptosis is closely related to the occurre

Keywords/Topics
nerve regeneration; painful mechanical sensibility; electronic von frey algesimeter; puerarin; functional recovery; peripheral nerve injury; acsl4-dependent ferroptosis; poor treatment efficacy; ferroptosis; sensory function recovery

Source :

https://www.sciencedirect.com/science/article/pii/S0141813026013309

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