Single-nucleus rna sequencing identifies universal camk1d upregulation and dysregulated c-ltmr subtypes as key drivers of paclitaxel-induced neuropathy

Authors
Sun, Wuping, Li, Rongzhen, Zhang, Xinyi, Wu, Songbin, Jiang, Yanjun, Li, Qian, Cao, Di, Xiong, Donglin, Xiao, Lizu, Liu, Xiaodong


Lab

Journal
Cell Biology and Toxicology

Abstract
Neuropathic pain triggered by chemotherapy poses a significant clinical challenge. Investigating cell type-specific alterations through single-cell transcr

Keywords/Topics
Chemotherapy-induced peripheral neuropathy; Paclitaxel-induced peripheral neuropathy; Mechanical allodynia; Thermal hyperalgesia; Cold hyperalgesia; Single nuclei RNA sequencing

BIOSEB Instruments Used:
Cold Hot Plate Test (BIO-CHP)

Source :

https://link.springer.com/article/10.1007/s10565-025-10065-z

Related products

Cold Hot Plate Test

Publication request

Thank you for your interest in our product range and your request for this publication, which will be sent to you if the research team and the journal allow it. Our commercial team will contact you as soon as possible.