The extracellular heparan sulfatase SULF2 limits myeloid IFNBeta signaling and Th17 responses in inflammatory arthritis

Authors
Swart, Maarten, Redpath, Andia N., Ogbechi, Joy, Cardenas, Ryan, Topping, Louise, Compeer, Ewoud B., Goddard, Michael, Chanalaris, Anastasios, Williams, Richard, Brewer, Daniel S., Smart, Nicola, Monaco, Claudia, Troeberg, Linda


Lab

Journal
Cellular and Molecular Life Sciences

Abstract
Heparan sulfate (HS) proteoglycans are important regulators of cellular responses to soluble mediators such as chemokines, cytokines and growth factors. We

Keywords/Topics
Heparan sulfate;Interferon; Inflammation; Macrophage

BIOSEB Instruments Used:
Dynamic Weight Bearing 2.0 (BIO-DWB-DUAL)

Source :

https://link.springer.com/article/10.1007/s00018-024-05333-w

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