Niclosamide extends health span and reduces frailty by ameliorating mTORC1 hyperactivation in aging models

Authors
Pyeong Geun Choi, Hee Soo Kim, So-Hyun Park, Hyo-Deok Seo, Jeong-Hoon Hahm, Yang Hoon Huh, Tae-Il Jeon, Jiyun Ahn, Chang Hwa Jung


Lab

Journal
Journal of Advanced Research

Abstract
Frailty is characterized by an increased vulnerability to disease and physical debilitation due to a decline in the body’s capacity to maintain homeos…

Keywords/Topics
Aging;Caenorhabditis elegans;Health span;Longevity;Sarcopenia;Skeletal muscle

BIOSEB Instruments Used:
Grip strength test (BIO-GS4)

Source :

https://www.sciencedirect.com/science/article/pii/S2090123225002711

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