Obesity-induced emotional alterations in mice are associated with impairments of tryptophan metabolism along the kynurenine and indole pathways

Authors
Nathalie Castanon, Sylvie Vancassel, Camille Amadieu, Sofia Cussotto, Quentin Leyrolle, Céline Lucas, Antoine Lefevre, Patrick Emond, Anne-Laure Dinel, Lucile Capuron


Lab

Journal
Brain, Behavior, and Immunity

Abstract
Chronic inflammatory conditions, such as obesity, are frequently associated with a high prevalence of mood disorders and a reduced response to convent…

Keywords/Topics
Mood disorders;Neuroinflammation;Obesity;Peripheral and brain tryptophan metabolism;Kynurenine pathway;Indoles;Emotional behaviors;Metabolomics;Preclinical study

BIOSEB Instruments Used:
Smart 3.0 - Video Tracking System (SMART30)

Source :

https://www.sciencedirect.com/science/article/pii/S0889159125003496

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