Flexibility as a marker of early cognitive decline in humanized apolipoprotein E ε4 (ApoE4) mice

Authors
MATHIEU BOUCHER


Lab
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Journal
Neurobiology of Aging

Abstract
To test the hypothesis that ApoE4 may be involved in cognitive deficits associated with aging, we investigated the impact of APOE4 status and aging on the flexibility and memory components of spatial learning in mice. Young adult (6 months) and

Keywords/Topics
mice; each mouse s trajectory; several sensorimotor tests; early cognitive decline; that; apoe4; cognitive deficits; aging; apoe4 status; spatial learning

Source :

https://www.academia.edu/download/131892246/AcceptedPaper_Schmitt_20et_20al_2020-12-18.pdf

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