Targeted Delivery of Pioglitazone to Neuronal Mitochondria Using Mito-2-Deoxyglucose Dendrimer Augments Neuroprotection After Traumatic Brain Injury

Authors
Dhull, Anubhav, Zhang, Zhi, Dar, Aqib Iqbal, Wei, Jing, Sharma, Rishi, Mashal, Yara, Naseer, Zahrah, O’Brien, Alivia, Wu, Jason, Sharma, Anjali


Lab

Journal
Acta Materialia, Inc.

Abstract
Traumatic brain injury (TBI) triggers mitochondrial dysfunction and oxidative stress, driving progressive neuronal damage and long-term neurological deficits. E

Keywords/Topics
Mitochondria Targeting; Pioglitazone; Drug Delivery; Neuronal Delivery; Dendrimer; Traumatic Brain Injury; SSRN; Anubhav Dhull; Zhi Zhang; Aqib Iqbal Dar; Jing Wei; Rishi Sharma; Yara Mashal; Zahrah Naseer; Alivia O’Brien; Jason Wu; Anjali Sharma

Source :

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=7116718

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