S-nitrosoglutathione reductase alleviates morphine analgesic tolerance by restricting PKCAlpha S-nitrosation

Authors
Ling-Yan Su, Lijin Jiao, Qianjin Liu, Xinhua Qiao, Ting Xie, Zhiyu Ma, Min Xu, Mao-Sen Ye, Lu-Xiu Yang, Chang Chen, Yong-Gang Yao


Lab

Journal
Redox Biology

Abstract
Morphine, a typical opiate, is widely used for controlling pain but can lead to various side effects with long-term use, including addiction, analgesi

Keywords/Topics
s-nitrosoglutathione;reductase;alleviates;morphine;analgesic;tolerance;restricting;s-nitrosation;typical;opiate

BIOSEB Instruments Used:
Rodent pincher - Analgesia meter - Wireless (BIO-RP-WRS)

Source :

https://www.sciencedirect.com/science/article/pii/S2213231724002179

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