Revisiting MAC as a static measure of anaesthesia: evidence for dynamic responses under isoflurane in male mice

Authors
Aden Mandel, Jackson Soohoo, Chloe Deitelzweig, Isha Patkar, Dennis Han, Madona Farag, Andrew McKinstry-Wu


Lab
Laboratory Investigation

Journal
British Journal of Anaesthesia

Abstract
The presence of a righting reflex is known to vary over time in an individual at the population half-maximal effective anaesthetic concentration (EC50

Keywords/Topics
male mice; half-maximal effective anaesthetic concentration; calibrated forceps; anaesthesia; evidence; dynamic responses; isoflurane; time; ec50 paw pinches; bioseb

Source :

https://www.sciencedirect.com/science/article/pii/S0007091226001819

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