Neuropathic pain - page 6 Scientific Publications

Latest publication 01/01/2026

GPRASP1 deletion suppresses antinociceptive tolerance during chronic activation

Delta-opioid receptor (DOR) agonists display antinociceptive properties with less adverse effects than morphine derivatives and other opioids targetin

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    [title] => GPRASP1 deletion suppresses antinociceptive tolerance during chronic activation 
    [paragraph] => GPRASP1 deletion suppresses antinociceptive tolerance during chronic activation of delta opioid receptor in persistent pain
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Authors
Juliette Kaeffer, Marie-Laure Straub, Glenn-Marie Le Coz, Raphaëlle Quillet, Valérie Kugler, Nathalie Petit-Demoulière, Manon Gerum, Gabrielle Zeder-Lutz, Stéphane Doridot, Michael Dumas, Johana Chicher, Philippe Hammann, Philippe Marin, Franck Vandermoere, Dominique Massotte, Frédéric Simonin, Sandra Lecat

Lab
Journal
Biomedicine & Pharmacotherapy
Abstract
Delta-opioid receptor (DOR) agonists display antinociceptive properties with less adverse effects than morphine derivatives and other opioids targetin
Keywords/Topics
persistent pain delta-opioid receptor; gprasp1 deletion; antinociceptive tolerance; chronic activation; delta; opioid receptor; agonists; antinociceptive properties; less adverse effects; morphine derivatives
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A fast and accurate algometer based on an instrumented pincher as an alternative to the Randall-Selitto test: This new analgesia meter developed by Bioseb following Luis-Delgado et al. (2005) allows accurate nociceptive tests to measure mechanical pain threshold on rat or mouse limbs with minimal constraint. Now wireless, to be free from annoying cables!

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