Alzheimer disease - page 1 Scientific Publications

Latest publication 03/01/2025

Social and contextual memory impairments induced by Amyloid-β oligomers are r

Sigma-1 receptors (S1Rs) are widely expressed throughout the central nervous system and modulate neuron intracellular calcium levels, leading to...

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    [title] => Social and contextual memory impairments induced by Amyloid-β oligomers are r
    [paragraph] => Social and contextual memory impairments induced by Amyloid-β oligomers are rescued by Sigma-1 receptor activation
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Authors
Souhail Djebari, Raquel Jiménez-Herrera, Guillermo Iborra-Lázaro, Lydia Jiménez-Díaz, Juan D. Navarro-López



 Lab


Journal
Biomedicine & Pharmacotherapy


Abstract
Sigma-1 receptors (S1Rs) are widely expressed throughout the central nervous system and modulate neuron intracellular calcium levels, leading to chang…


Keywords/Topics
Alzheimer’s disease;Amyloid-β oligomers;Social memory;Spatial memory;Hippocampus;Sigma-1;PRE-084;LTP
BIOSEB Instruments Used:
Tail Suspension Test - Wireless (BIO-TST5)

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Bioseb's version 5 of the Tail Suspension Test system, based on both strain sensors and video acquisition, is the only fully automatic solution in the world for running a simple and objective despair test on mice. It is a fast, painless, and reliable way for testing psychotropic effects from stimulant doses of drugs such as anti-depressants and sedatives. This classic and painless research test for anxiety and depression is now offered with a new, powerful and modern software, in a wireless, bluetooth-based version.


Instrument for mice

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