Publications

Latest publication 12/18/2024

Engineered self-regulating macrophages for targeted anti-inflammatory drug deliv

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by increased levels of inflammation that primarily manifests in the...

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    [title] => Engineered self-regulating macrophages for targeted anti-inflammatory drug deliv
    [paragraph] => Engineered self-regulating macrophages for targeted anti-inflammatory drug delivery
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Authors
Klimak, Molly, Cimino, Amanda, Lenz, Kristin L., Springer, Luke E., Collins, Kelsey H., Harasymowicz, Natalia S., Xu, Nathan, Pham, Christine T.N., Guilak, Farshid



 Lab


Journal
Arthritis Research & Therapy


Abstract
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by increased levels of inflammation that primarily manifests in the joints. Macrop


Keywords/Topics
Cell therapy ;Rheumatoid arthritis; Designer cell ;Synthetic biology 
BIOSEB Instruments Used:
SMALGO: SMall animal ALGOmeter - Wireless (BIO-SMALGO-WRS)

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Dedicated to small animals, like mice and rats, Smalgo is a pressure-based analgesimeter designed for easy assessment of sensitivity threshold. It is a must for osteo-arthritis and pain studies. A quick, easy-to-use and reliable instrument to assess threshold sensitivity of the animal when applying a progressive force, which can also be used for drug screening, phenotyping, as well as on studies about neuropathy, inflammation and post-operative pain. Now wireless, to be free from annoying cables!


Instrument for ratsInstrument for mice

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