Publications

Latest publication 11/01/2026

Interactions between SSR504734, a selective glycine transporter type 1 inhibitor

Studies suggest the potential involvement of glycine in seizures and epilepsy; however, no currently available antiseizure medications directly target

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    [title] => Interactions between SSR504734, a selective glycine transporter type 1 inhibitor
    [paragraph] => Interactions between SSR504734, a selective glycine transporter type 1 inhibitor, and antiseizure drugs: pharmacodynamic and pharmacokinetic studies in mice
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Authors
Nikola Gapińska, Piotr Wlaź, Elżbieta Wyska, Artur Świerczek, Krzysztof Kamiński, Marcin Jakubiec, Katarzyna Ciepiela, Michał Abram, Gniewomir Latacz, Ewa Poleszak, Katarzyna Socała

Lab
Journal
Neuropharmacology
Abstract
Studies suggest the potential involvement of glycine in seizures and epilepsy; however, no currently available antiseizure medications directly target
Keywords/Topics
mice studies; interactions; ssr504734; antiseizure drugs; pharmacodynamic and pharmacokinetic studies; glycine; seizures; epilepsy; studies; glycine transporter
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An easy way to objectively quantify the muscular strength of mice and rats, and to assess the effect of drugs, toxins, muscular (i.e. myopathy) and neurodegenerative diseases on muscular degeneration. It is widely used in conjunction with the ROTAROD motor coordination test: a normally coordinated rodent will show a decreased latency to fall off the rotating rod if its muscular strength is low. The Grip Strength Test is a must for your research on activity, motor control & coordination, and is particularly well suited for studies on Parkinson's & Huntington's disease.
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