Publications

Latest publication 04/01/2019

Intra-articular treatment with triamcinolone acetonide-loaded liposomes in the r

Local intra-articular injections with triamcinolone acetonide (TA) is favorable as an anti-inflammatory treatment. In animal (rat) models of OA it...

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    [title] => Intra-articular treatment with triamcinolone acetonide-loaded liposomes in the r
    [paragraph] => Intra-articular treatment with triamcinolone acetonide-loaded liposomes in the rat high-fat diet groove model
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Authors
NM Korthagen, HM de Visser, G Geusebroek, G Storm et al

 Lab
Utrecht Univ., Utrecht, Netherlands
Journal
Osteoarthritis and Cartilage
Abstract
Local intra-articular injections with triamcinolone acetonide (TA) is favorable as an anti-inflammatory treatment. In animal (rat) models of OA it was shown that TA can reduce osteophyte formation and thus may be beneficial as a disease modifying treatment. To evaluate the potential for slow-release anti-inflammatory treatment in a model mimicking metabolically accelerated post-traumatic OA, we evaluated the effect of TA-loaded liposomes, in the high-fat diet groove model in rats.
BIOSEB Instruments Used
Dynamic Weight Bearing 2.0 (BIO-DWB-DUAL)
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